Author

Boobalan Pachaiyappan

University of Virginia - Cited by 354 - Medicinal Chemistry - Drug Discovery - Computer-aided drug design

Biography

Dr. Boobalan Pachaiyappan  is an Associate professor in the department of Medicinal Chemistry Drug Discovery University of Virginia Charlottesville, VA, United States. His study interests major on Medicinal Chemistry Drug Discovery. Currently , Dr. Boobalan Pachaiyappan  is the author/editors/reviewer in several international journals. He published 5 articles in many journals and the articles are informative and got good citations.
Title
Cited by
Year
Low molecular weight amidoximes that act as potent inhibitors of lysine-specific demethylase 1
S Hazeldine, B Pachaiyappan, N Steinbergs, S Nowotarski, AS Hanson, ...Journal of medicinal chemistry 55 (17), 73-7391, 2012201
78
2012
Antibacterial diamines targeting bacterial membranes
B Wang, B Pachaiyappan, JD Gruber, MG Schmidt, YM Zhang, PM WosterJournal of medicinal chemistry 59 (7), 3140-3151, 2016201
61
2016
Transcriptional activity of the islet β cell factor Pdx1 is augmented by lysine methylation catalyzed by the methyltransferase Set7/9
AV Maganti, B Maier, SA Tersey, ML Sampley, AL Mosley, S Özcan, ...Journal of Biological Chemistry 290 (15), 9812-9822, 2015201
50
2015
Structure–activity study for (bis) ureidopropyl-and (bis) thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures
SL Nowotarski, B Pachaiyappan, SL Holshouser, CJ Kutz, Y Li, Y Huang, ...Bioorganic & medicinal chemistry 23 (7), 1601-1612, 2015201
47
2015
Design of small molecule epigenetic modulators
B Pachaiyappan, PM WosterBioorganic & medicinal chemistry letters 24 (1), 21-32, 2014201
39
2014
Interrogating alkyl and arylalkylpolyamino (bis) urea and (bis) thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum …
BK Verlinden, M De Beer, B Pachaiyappan, E Besaans, WA Andayi, ...Bioorganic & medicinal chemistry 23 (16), 5131-5143, 2015201
25
2015
Molecular modeling, synthesis, and activity studies of novel biaryl and fused-ring BACE1 inhibitors
SR Chirapu, B Pachaiyappan, HF Nural, X Cheng, H Yuan, DC Lankin, ...Bioorganic & medicinal chemistry letters 19 (1), 264-274, 2009200
22
2009
Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid
H Lee, HV Le, R Wu, E Doud, R Sanishvili, JF Kellie, PD Compton, ...ACS chemical biology 10 (9), 2087-2098, 2015201
17
2015
Structure-and Ligand-Based Modeling of Beta-Secretase 1 (BACE1) Inhibitors
B PachaiyappanUniversity of Illinois at Chicago, 01101
2
2011
Corrigendum to “Structure–activity study for (bis) ureidopropyl-and (bis) thioureidopropyldiamine LSD1 inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures”[Bioorg …
Corrigendum to “Structure–activity study for (bis) ureidopropyl-and (bis) thioureidopropyldiamine LSD inhibitors with 3-5-3 and 3-6-3 carbon backbone architectures”[Bioorg …SL Nowotarski, B Pachaiyappan, SL Holshouser, CJ Kutz, Y Li, Y Huang, ...Bioorganic and Medicinal Chemistry 26 (2), 3728-3729, 20820
1
2018