Author

Timothy J. Hagen

Northern Illinois University - Cited by 2,645 - medicinal chemistry - organic chemistry

Biography

Dr. Timothy J. Hagen  is an Associate professor in the department ofmedicinal chemistry Northern Illinois University. His study interests major onmedicinal chemistry. Currently , Dr. Timothy J. Hagen  is the author/editors/reviewer in several international journals. He published 5 articles in many journals and the articles are informative and got good citations.
Title
Cited by
Year
Demonstration of AutoDock as an educational tool for drug discovery
TR Helgren, TJ HagenJournal of chemical education 94 (3), 345-349, 2017201
54
2017
Discovery of triazines as selective PDE4B versus PDE4D inhibitors
TJ Hagen, X Mo, AB Burgin, D Fox 3rd, Z Zhang, ME GurneyBioorganic & medicinal chemistry letters 24 (16), 4031-4034, 2014201
44
2014
The synthesis, antimalarial activity and CoMFA analysis of novel aminoalkylated quercetin analogs
TR Helgren, RJ Sciotti, P Lee, S Duffy, VM Avery, O Igbinoba, M Akoto, ...Bioorganic & medicinal chemistry letters 25 (2), 327-332, 2015201
41
2015
Design and synthesis of selective phosphodiesterase 4D (PDE4D) allosteric inhibitors for the treatment of fragile X syndrome and other brain disorders
ME Gurney, RA Nugent, X Mo, JA Sindac, TJ Hagen, D Fox III, ...Journal of medicinal chemistry 62 (10), 4884-4901, 2019201
40
2019
Heteroaryl inhibitors of PDE4
ME Gurney, TJ Hagen, X Mo, AS Vellekoop, DL Romero, RF Campbell, ...US Patent 9,221,843, 2015201
31
2015
Discovery of Inhibitors of Burkholderia pseudomallei Methionine Aminopeptidase with Antibacterial Activity
P Wangtrakuldee, MS Byrd, CG Campos, MW Henderson, Z Zhang, ...ACS medicinal chemistry letters 4 (8), 699-703, 2013201
23
2013
Synthesis and biological evaluation of pyrazolopyrimidines as potential antibacterial agents
GM Goshu, D Ghose, JM Bain, PG Pierce, DW Begley, SN Hewitt, ...Bioorganic & medicinal chemistry letters 25 (24), 5699-5704, 202
15
2015
Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei
Z Zhang, S Jakkaraju, J Blain, K Gogol, L Zhao, RC Hartley, CA Karlsson, ...Bioorganic & medicinal chemistry letters 23 (24), 6860-6863, 2013201
15
2013
A concise synthesis of biaryl PDE4D allosteric modulators
A Dalby, X Mo, R Stoa, N Wroblewski, Z Zhang, TJ HagenTetrahedron Letters 54 (21), 2737-2739, 2013201
12
2013
Dissemination of Imidacloprid Through Dairy Cattle Manure and Its Effect on the Biological Control Agent, Spalangia endius (Hymenoptera: Pteromalidae), and a Filth Fly Host …
ER Burgess IV, SM Watkins, BH King, K Chantos-Davidson, AN Kremer, ...Journal of economic entomology 112 (2), 974-980, 2019201
10
2019
Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents
TR Helgren, C Chen, P Wangtrakuldee, TE Edwards, BL Staker, ...Bioorganic & medicinal chemistry 25 (3), 813-824, 2017201
10
2017
Timed release of substances to treat ocular disorders
E Gaillard, J Dillon, J Friedrichs, T Xu, TJ Hagen, DK KarumanchiUS Patent 9,962,333, 2018201
5
2018
Traditional Kenyan herbal medicine: exploring natural products’ therapeutics against schistosomiasis
FK Ndegwa, C Kondam, SY Aboagye, TE Esan, ZS Waxali, ME Miller, ...Journal of helminthology 96, e16, 2022202
4
2022
Heteroaryl inhibitors of PDE4
Heteroaryl inhibitors of PDEME Gurney, TJ Hagen, X Mo, AS Vellekoop, DL Romero, RF Campbell, ...US Patent 9,777,02, 2017201
4
2017
Compound D159687, a phosphodiesterase 4D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive function
Compound D159687, a phosphodiesterase D inhibitor, induces weight and fat mass loss in aged mice without changing lean mass, physical and cognitive functionIM Muo, SJ Park, A Smith, DA Springer, MD Allen, TJ Hagen, JH ChungBiochemical and biophysical research communications 506 (), 1059-106, 2018201
4
2018
The identification of inhibitory compounds of Rickettsia prowazekii methionine aminopeptidase for antibacterial applications
TR Helgren, ES Seven, C Chen, TE Edwards, BL Staker, J Abendroth, ...Bioorganic & medicinal chemistry letters 28 (8), 176-180, 2018201
3
2018
Heteroaryl inhibitors of PDE4
ME Gurney, TJ Hagen, X Mo, AS Vellekoop, DL Romero, RF Campbell, ...US Patent 10,09,686, 2018201
3
2018
Biaryl PDE4 inhibitors for treating inflammatory, cardiovascular and CNS disorders
J Singh, ME Gurney, A Burgin, V Sandanayaka, A Kiselyov, A Motta, ...US Patent 8,791,67, 01401
2
2014
Biaryl pde4 inhibitors for treating pulmonary and cardiovascular disorders
J Singh, ME Gurney, A Burgin, A Kiselyov, M Rao, T HagenUS Patent App. 13/457,716, 010
2
2012
(Z)-4-Chloro-N-{3-[(4-chlorophenyl) sulfonyl]-2, 3-dihydrobenzo [d] thiazol-2-ylidene} benzenesulfonamide
(Z)-4-Chloro-N-{3-[(4-chlorophenyl) sulfonyl]-, 3-dihydrobenzo [d] thiazol--ylidene} benzenesulfonamideSM Watkins, TJ Hagen, TS Perkins, C ZhengIUCrData (6), x170865, 01701
2
2017