Author

Kyle S. McCommis

Saint Louis University School of Medicine - Cited by 4,369 - Metabolism - diabetes - heart failure

Biography

I am Kyle  S. McCommis, belonging to Department of Biomedical Sciences, University of Missouri, Columbia, MO, USA. Interested in the field of Bioenergetics, mitochondrial metabolism.
Title
Cited by
Year
Nutritional modulation of heart failure in mitochondrial pyruvate carrier–deficient mice
KS McCommis, A Kovacs, CJ Weinheimer, TM Shew, TR Koves, ...Nature metabolism 2 (11), 1232-1247, 2020202
73
2020
The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesity
S Gao, S Ghoshal, L Zhang, JR Stevens, KS McCommis, BN Finck, ...Journal of Biological Chemistry 294 (36), 13366-13377, 2019201
55
2019
NADPH and glutathione redox link TCA cycle activity to endoplasmic reticulum homeostasis
ER Gansemer, KS McCommis, M Martino, AQ King-McAlpin, MJ Potthoff, ...Iscience 23 (5), 2020202
35
2020
Treating hepatic steatosis and fibrosis by modulating mitochondrial pyruvate metabolism
KS McCommis, BN FinckCellular and molecular gastroenterology and hepatology 7 (2), 275-284, 2019201
34
2019
Hepatic stellate cells in physiology and pathology
DR Kamm, KS McCommisThe Journal of Physiology 600 (8), 1825-1837, 2022202
30
2022
Loss of lipin 1–mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice
GG Schweitzer, SL Collier, Z Chen, KS McCommis, SK Pittman, J Yoshino, ...The FASEB Journal 33 (1), 652, 2019201
29
2019
The impact of diet‐induced hepatic steatosis in a murine model of hepatic ischemia/reperfusion injury
KHH Liss, KS McCommis, KT Chambers, TA Pietka, GG Schweitzer, ...Liver Transplantation 24 (7), 908-921, 2018201
23
2018
Hepatocyte expression of the micropeptide adropin regulates the liver fasting response and is enhanced by caloric restriction
S Banerjee, S Ghoshal, JR Stevens, KS McCommis, S Gao, ...Journal of Biological Chemistry 295 (40), 13753-13768, 2020202
22
2020
Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide
DR Kamm, KD Pyles, MC Sharpe, LN Healy, JR Colca, KS McCommisJournal of Biological Chemistry 296, 2021202
19
2021
The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism
PA Vigueira, KS McCommis, WT Hodges, GG Schweitzer, SL Cole, ...Experimental physiology 102 (8), 985-999, 2017201
16
2017
Fructose promotes cytoprotection in melanoma tumors and resistance to immunotherapy
LM Kuehm, N Khojandi, A Piening, LE Klevorn, SC Geraud, ...Cancer immunology research 9 (2), 227-238, 2021202
16
2021
PPARα agonist fenofibrate attenuates iron-induced liver injury in mice by modulating the Sirt3 and β-catenin signaling
A Mandala, WJ Chen, A Armstrong, MR Malhotra, S Chavalmane, ...American Journal of Physiology-Gastrointestinal and Liver Physiology 321 (3 …, 2021202
15
2021
Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice
WT Hodges, C Jarasvaraparn, D Ferguson, K Griffett, LE Gill, Y Chen, ...Journal of Biological Chemistry 298 (2), 2022202
14
2022
Inhibition of the mitochondrial pyruvate carrier by tolylfluanid
Y Chen, KS McCommis, D Ferguson, AM Hall, CA Harris, BN FinckEndocrinology 159 (2), 609-621, 2018201
12
2018
Hepatic monoacylglycerol acyltransferase 1 is induced by prolonged food deprivation to modulate the hepatic fasting response [S]
AJ Lutkewitte, KS McCommis, GG Schweitzer, KT Chambers, MJ Graham, ...Journal of lipid research 60 (3), 528-538, 2019201
11
2019
Monoacylglycerol acyltransferase 1 knockdown exacerbates hepatic ischemia/reperfusion injury in mice with hepatic steatosis
KHH Liss, SE Ek, AJ Lutkewitte, TA Pietka, M He, P Skaria, E Tycksen, ...Liver Transplantation 27 (1), 116-133, 2021202
10
2021
Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids
MR Martino, M Gutiérrez-Aguilar, NKH Yiew, AJ Lutkewitte, JM Singer, ...Cell reports 39 (4), 2022202
10
2022
Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations
KT Chambers, MA Cooper, AR Swearingen, RT Brookheart, ...JCI insight 6 (), 2021202
9
2021
The importance of keeping time in the liver
KS McCommis, AA ButlerEndocrinology 162 (2), bqaa230, 2021202
8
2021
Identification of novel mitochondrial pyruvate carrier inhibitors by homology modeling and pharmacophore-based virtual screening
L Hegazy, LE Gill, KD Pyles, C Kaiho, S Kchouk, BN Finck, KS McCommis, ...Biomedicines 10 (2), 35, 2022202
6
2022