Author

Hernando Lopez-Bertoni

Johns Hopkins School of Medicine - Cited by 894 - Neuro-Oncology

Biography

Dr. Hernando Lopez-Bertoni is an Experienced Assistant Professor with a demonstrated history of working in the Higher Education industry. Skilled in Cancer Research, development of molecular therapeutics, Molecular & Cellular Biology, Flow Cytometry, Immunocytochemistry, and Cancer Stem Cells. Strong education professional with a Bachelor of Science - BS focused in Microbiology, from Kansas State University and a PhD in Cancer Biology from the University of Nebraska Medical Center.
Title
Cited by
Year
Bioreducible polymeric nanoparticles containing multiplexed cancer stem cell regulating miRNAs inhibit glioblastoma growth and prolong survival
H Lopez-Bertoni, KL Kozielski, Y Rui, B Lal, H Vaughan, DR Wilson, ...Nano letters 18 (7), 4086-4094, 2018201
117
2018
Epigenetic modulation of a miR-296-5p: HMGA1 axis regulates Sox2 expression and glioblastoma stem cells
H Lopez-Bertoni, B Lal, N Michelson, H Guerrero-Cazares, ...Oncogene 35 (37), 4903-4913, 2016201
61
2016
A Sox2: miR-486-5p axis regulates survival of GBM cells by inhibiting tumor suppressor networks
H Lopez-Bertoni, IS Kotchetkov, N Mihelson, B Lal, Y Rui, H Ames, ...Cancer research 80 (8), 1644-1655, 2020202
40
2020
Extracellular matrix protein tenascin C increases phagocytosis mediated by CD47 loss of function in glioblastoma
D Ma, S Liu, B Lal, S Wei, S Wang, D Zhan, H Zhang, RS Lee, P Gao, ...Cancer research 79 (10), 2697-2708, 2019201
39
2019
Crizotinib and erlotinib inhibits growth of c-Met+/EGFRvIII+ primary human glioblastoma xenografts
CR Goodwin, P Rath, O Oyinlade, H Lopez, S Mughal, S Xia, Y Li, H Kaur, ...Clinical neurology and neurosurgery 171, 26-33, 2018201
23
2018
TET1 deficiency attenuates the DNA damage response and promotes resistance to DNA damaging agents
JB Coulter, H Lopez-Bertoni, KJ Kuhns, RS Lee, J Laterra, JP BresslerEpigenetics 12 (10), 854-864, 2017201
22
2017
Sox2 induces glioblastoma cell stemness and tumor propagation by repressing TET2 and deregulating 5hmC and 5mC DNA modifications
H Lopez-Bertoni, A Johnson, Y Rui, B Lal, S Sall, M Malloy, JB Coulter, ...Signal transduction and targeted therapy 7 (1), 37, 222
20
2022
Mutant IDH1 promotes phagocytic function of microglia/macrophages in gliomas by downregulating ICAM1
D Ma, D Zhan, Y Fu, S Wei, B Lal, J Wang, Y Li, H Lopez-Bertoni, F Yalcin, ...Cancer letters 517, 35-45, 2021202
13
2021
Analysis of SOX2-regulated transcriptome in glioma stem cells
AM Acanda de la Rocha, H Lopez-Bertoni, E Guruceaga, ...PloS one 11 (9), e0163155, 2016201
13
2016
miR-425-5p, a SOX2 target, regulates the expression of FOXJ3 and RAB31 and promotes the survival of GSCs
AMA de la Rocha, M González-Huarriz, E Guruceaga, N Mihelson, ...Archives of clinical and biomedical research 4 (3), 221, 2020202
11
2020
TET1 regulates DNA repair in human glial cells
KJ Kuhns, H Lopez-Bertoni, JB Coulter, JP BresslerToxicology and applied pharmacology 380, 114646, 2019201
7
2019
Exploring glioblastoma stem cell heterogeneity: Immune microenvironment modulation and therapeutic opportunities
AL Johnson, J Laterra, H Lopez-BertoniFrontiers in Oncology 12, 99498, 2022202
5
2022
Opinion: miRNAs–The new wave of molecular cancer therapeutics
H Lopez-Bertoni, J LaterraTranslational Oncology 14 (6), 101064, 2021202
3
2021
Targeting UDP-α-d-glucose 6-dehydrogenase alters the CNS tumor immune microenvironment and inhibits glioblastoma growth
D Zhan, F Yalcin, D Ma, Y Fu, S Wei, B Lal, Y Li, O Dzaye, J Laterra, ...Genes & Diseases 9 (), 717-70, 2022202
3
2022
Stem-03. Oct4/Sox2 drive an immunosuppressive gsc phenotype by inducing T-reg effector genes Via Tgfbr2 signaling
Stem-03. Oct4/Sox drive an immunosuppressive gsc phenotype by inducing T-reg effector genes Via Tgfbr signalingA Johnson, J Korleski, J Laterra, H Lopez-BertoniNeuro-Oncology 3 (Supplement_6), vi1-vi, 010
2
2021
Monoallelic IDH1 R132H mutation mediates glioma cell response to anticancer therapies via induction of senescence
Monoallelic IDH R32H mutation mediates glioma cell response to anticancer therapies via induction of senescenceD Zhan, D Ma, S Wei, B Lal, Y Fu, C Eberhart, J Laterra, M Ying, Y Li, ...Molecular Cancer Research 9 (), 878-888, 20220
1
2021
Vitamin C enhances H3K36me3 via NSD1 promoter demethylation and sensitizes GBM stem cells to DNA damaging agents
Vitamin C enhances H3K36me3 via NSD promoter demethylation and sensitizes GBM stem cells to DNA damaging agentsH Khela, S Sudhir, M Fagundo-Lugo, B Lal, J Laterra, H Lopez-BertoniCancer Research 8 (3_Supplement), 224-224, 20220
1
2021