Author

Akiko Kumagai

California Institute of Technology - Cited by 11,726

Biography

We examined the etiology of hyperkeratosis of the oral mucosa, focusing on antioxidant actions and oxidative stress related to the accumulation of oxidized and damaged molecules.
Title
Cited by
Year
Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation
KM Sakamoto, KB Kim, A Kumagai, F Mercurio, CM Crews, RJ DeshaiesProceedings of the National Academy of Sciences 98 (15), 8554-8559, 2001200
2001
TopBP1 activates the ATR-ATRIP complex
A Kumagai, J Lee, HY Yoo, WG DunphyCell 124 (5), 943-955, 2006200
883
2006
Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15
PR Mueller, TR Coleman, A Kumagai, WG DunphyScience 270 (5233), 86-90, 1995199
866
1995
The cdc25 protein contains an intrinsic phosphatase activity
WG Dunphy, A KumagaiCell 67 (1), 189-196, 1991199
735
1991
660
1996
Regulation of the cdc25 protein during the cell cycle in Xenopus extracts
A Kumagai, WG DunphyCell 70 (1), 139-151, 1992199
540
1992
Positive regulation of Wee1 by Chk1 and 14-3-3 proteins
J Lee, A Kumagai, WG DunphyMolecular biology of the cell 12 (3), 551-563, 2001200
368
2001
The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR
J Lee, A Kumagai, WG DunphyJournal of Biological Chemistry 282 (38), 28036-28044, 2007200
347
2007
The Xenopus Chk1 Protein Kinase Mediates a Caffeine-sensitive Pathway of Checkpoint Control in Cell-free Extracts
A Kumagai, Z Guo, KH Emami, SX Wang, WG DunphyThe Journal of cell biology 142 (6), 1559-1569, 1998199
296
1998
14-3-3 Proteins Act as Negative Regulators of the Mitotic Inducer Cdc25 in Xenopus Egg Extracts
A Kumagai, PS Yakowec, WG DunphyMolecular biology of the cell 9 (2), 345-354, 1998199
286
1998
Treslin collaborates with TopBP1 in triggering the initiation of DNA replication
A Kumagai, A Shevchenko, A Shevchenko, WG DunphyCell 140 (3), 349-359, 2010201
254
2010
Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase
HY Yoo, A Kumagai, A Shevchenko, A Shevchenko, WG DunphyCell 117 (5), 575-588, 2004200
249
2004
Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1
A Kumagai, WG DunphyNature cell biology 5 (2), 161-165, 2003200
190
2003
Molecular genetic analysis of two G alpha protein subunits in Dictyostelium.
A Kumagai, JA Hadwiger, M Pupillo, RA FirtelJournal of Biological Chemistry 266 (2), 1220-1228, 1991199
188
1991
Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1
A Kumagai, SM Kim, WG DunphyJournal of Biological Chemistry 279 (48), 49599-49608, 2004200
182
2004