Author

Charles De Smet

de Duve Institute, Catholic University of Louvain - Cited by 7,951 - Cancer epigenetics

Biography

Dr Charles De Smet is currently working as a Faculty of Pharmacy and Biomedical Sciences at de Duve Institute, Université Catholique de Louvain, Brussels, Belgium. His research interest includes Homologous Recombination. Previously he worked in a PostDoc Position at Ludwig Institute for Cancer Research La Jolla, United States.
Title
Cited by
Year
DNA methylation is the primary silencing mechanism for a set of germ line-and tumor-specific genes with a CpG-rich promoter
C De Smet, C Lurquin, B Lethé, V Martelange, T BoonMolecular and cellular biology 19 (11), 7327-7335, 1999199
768
1999
Myc represses transcription through recruitment of DNA methyltransferase corepressor
C Brenner, R Deplus, C Didelot, A Loriot, E Viré, C De Smet, A Gutierrez, ...The EMBO journal 24 (2), 336-346, 2005200
562
2005
Characterization of the GAGE Genes That Are Expressed in Various Human Cancers and in Normal Testis
O De Backer, KC Arden, M Boretti, V Vantomme, C De Smet, S Czekay, ...Cancer research 59 (13), 3157-3165, 1999199
242
1999
Promoter-Dependent Mechanism Leading to Selective Hypomethylation within the 5′ Region of Gene MAGE-A1 in Tumor Cells
C De Smet, A Loriot, T BoonMolecular and cellular biology 24 (11), 4781-4790, 2004200
241
2004
Identification on a human sarcoma of two new genes with tumor-specific expression
V Martelange, C De Smet, E De Plaen, C Lurquin, T BoonCancer research 60 (14), 3848-3855, 2000200
174
2000
Oncogenic roles of DNA hypomethylation through the activation of cancer-germline genes
A Van Tongelen, A Loriot, C De SmetCancer letters 396, 130-137, 2017201
173
2017
MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription
S Laduron, R Deplus, S Zhou, O Kholmanskikh, D Godelaine, C De Smet, ...Nucleic acids research 32 (14), 4340-4350, 2004200
166
2004
Monoclonal anti-MAGE-3 CTL responses in melanoma patients displaying tumor regression after vaccination with a recombinant canarypox virus
V Karanikas, C Lurquin, D Colau, N Van Baren, C De Smet, B Lethé, ...The Journal of immunology 171 (9), 4898-4904, 2003200
136
2003
DNA hypomethylation in cancer: epigenetic scars of a neoplastic journey
C De Smet, A LoriotEpigenetics 5 (3), 206-213, 2010201
110
2010
Five new human cancer‐germline genes identified among 12 genes expressed in spermatogonia
A Loriot, T Boon, C De SmetInternational journal of cancer 105 (3), 371-376, 2003200
96
2003
Comparison of stable human Treg and Th clones by transcriptional profiling
J Stockis, W Fink, V François, T Connerotte, C De Smet, L Knoops, ...European journal of immunology 39 (3), 869-882, 2009200
92
2009
Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells
A Loriot, E De Plaen, T Boon, C De SmetJournal of Biological Chemistry 281 (15), 10118-10126, 2006200
89
2006
Expression of BORIS in melanoma: Lack of association with MAGE‐A1 activation
O Kholmanskikh, A Loriot, F Brasseur, E De Plaen, C De SmetInternational journal of cancer 122 (4), 777-784, 2008200
73
2008
CDKN2A, CDKN2B and p14 ARF are frequently and differentially methylated in ependymal tumours
E Rousseau, MM Ruchoux, F Scaravilli, F Chapon, M Vinchon, C De Smet, ...Neuropathology and applied neurobiology 29 (6), 574-583, 2003200
71
2003
A novel cancer-germline transcript carrying pro-metastatic miR-105 and TET-targeting miR-767 induced by DNA hypomethylation in tumors
A Loriot, A Van Tongelen, J Blanco, S Klaessens, J Cannuyer, ...Epigenetics 9 (8), 1163-1171, 2014201
70
2014
Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease
A Hendrickx, N Pierrot, B Tasiaux, O Schakman, P Kienlen-Campard, ...Plos One 9 (6), e99467, 2014201
68
2014
Subtelomeric DNA hypomethylation is not required for telomeric sister chromatid exchanges in ALT cells
G Tilman, A Loriot, A Van Beneden, N Arnoult, JA Londono-Vallejo, ...Oncogene 28 (14), 1682-1693, 2009200
66
2009
DNA hypomethylation and activation of germline-specific genes in cancer
C De Smet, A LoriotEpigenetic Alterations in Oncogenesis, 149-166, 2012201
53
2012
Photoreceptor proteins as cancer‐retina antigens
AV Bazhin, D Schadendorf, N Willner, C De Smet, A Heinzelmann, ...International journal of cancer 120 (6), 1268-1276, 2007200
51
2007
Interleukin-9–Induced Expression of M-Ras/R-Ras3 Oncogene in T-Helper Clones
J Louahed, L Grasso, C De Smet, E Van Roost, C Wildmann, ...Blood, The Journal of the American Society of Hematology 94 (5), 1701-1710, 1999199
42
1999

Referred From: https://scholar.google.com/citations?user=e_JjOYsAAAAJ&hl=en

Cited by
Citations 7951
h-index 33
i10-index 49
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