Author

Cheng Ting Chien

Distinguished Research Fellow, Academia Sinica - Cited by 7,284 - Molecular - Cell and Developmental Biology - Neuroscience - Genetics

Biography

Dr Cheng-Ting Chien is a Distinguished Research Fellow and the Deputy Director of Institute of Molecular Biology, and the coordinator of Neuroscience Program of Academia Sinica and Interdisciplinary Neuroscience Program of Taiwan International Graduate Program (TIGP) of Academia Sinica. His research has a long-term interest in neural development, using Drosophila sensory neurons as a model systems. His early studies focused on cell fate specification regulated by transcriptional factors, signalling pathways and protein degradation.
Title
Cited by
Year
A hedgehog-induced BTB protein modulates hedgehog signaling by degrading Ci/Gli transcription factor
Q Zhang, L Zhang, B Wang, CY Ou, CT Chien, J JiangDevelopmental cell 10 (6), 719-729, 2006200
261
2006
Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation
JT Wu, HC Lin, YC Hu, CT ChienNature cell biology 7 (10), 1014-1020, 2005200
210
2005
Functional cooperation between FACT and MCM helicase facilitates initiation of chromatin DNA replication
BCM Tan, CT Chien, S Hirose, SC LeeThe EMBO journal 25 (17), 3975-3985, 2006200
208
2006
LRRK2 G2019S mutation induces dendrite degeneration through mislocalization and phosphorylation of tau by recruiting autoactivated GSK3β
CH Lin, PI Tsai, RM Wu, CT ChienJournal of Neuroscience 30 (39), 13138-13149, 2010201
196
2010
F-box proteins: the key to protein degradation
MS Ho, PI Tsai, CT ChienJournal of biomedical science 13, 181-191, 2006200
182
2006
The utility F-box for protein destruction
MS Ho, C Ou, Y Chan, CT Chien, H PiCellular and Molecular Life Sciences 65, 1977-2000, 2008200
155
2008
Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c
YC Chen, HY Kuo, U Bornschein, H Takahashi, SY Chen, KM Lu, ...Nature neuroscience 19 (11), 1513-1522, 2016201
96
2016
Protection of cullin–RING E3 ligases by CSN–UBP12
JT Wu, YR Chan, CT ChienTrends in cell biology 16 (7), 362-369, 2006200
79
2006
DEN1 deneddylates non-cullin proteins in vivo
Y Chan, J Yoon, JT Wu, HJ Kim, KT Pan, J Yim, CT ChienJournal of cell science 121 (19), 3218-3223, 2008200
78
2008
Scabrous controls ommatidial rotation in the Drosophila compound eye
YH Chou, CT ChienDevelopmental Cell 3 (6), 839-850, 2002200
58
2002
The COP9 signalosome is required for light-dependent timeless degradation and Drosophila clock resetting
A Knowles, K Koh, JT Wu, CT Chien, DA Chamovitz, J BlauJournal of Neuroscience 29 (4), 11-1162, 2009200
52
2009
Lovastatin protects neurite degeneration in LRRK2-G2019S parkinsonism through activating the Akt/Nrf pathway and inhibiting GSK3β activity
CH Lin, HI Lin, ML Chen, TT Lai, LP Cao, MJ Farrer, RM Wu, CT ChienHuman molecular genetics 25 (10), 1965-1978, 2016201
48
2016
Actin blobs prefigure dendrite branching sites
V Nithianandam, CT ChienJournal of Cell Biology 217 (10), 3731-3746, 2018201
48
2018
Lrrk regulates the dynamic profile of dendritic Golgi outposts through the golgin Lava lamp
CH Lin, H Li, YN Lee, YJ Cheng, RM Wu, CT ChienJournal of Cell Biology 210 (3), 1-483, 2015201
47
2015
Control of protein degradation by E3 ubiquitin ligases in Drosophila eye development
CY Ou, H Pi, CT ChienTRENDS in Genetics 19 (7), 382-389, 2003200
46
2003
phyllopod is a target gene of proneural proteins in Drosophila external sensory organ development
H Pi, SK Huang, CY Tang, YH Sun, CT ChienProceedings of the National Academy of Sciences 101 (22), 8378-8383, 2004200
43
2004
Activity-dependent retrograde laminin A signaling regulates synapse growth at Drosophila neuromuscular junctions
PI Tsai, M Wang, HH Kao, YJ Cheng, YJ Lin, RH Chen, CT ChienProceedings of the National Academy of Sciences 109 (43), 17699-17704, 2012201
41
2012
Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth
PI Tsai, HH Kao, C Grabbe, YT Lee, A Ghose, TT Lai, KP Peng, ...Neural development 3, 1-17, 2008200
33
2008
Neurofibromin mediates FAK signaling in confining synapse growth at Drosophila neuromuscular junctions
PI Tsai, M Wang, HH Kao, YJ Cheng, JA Walker, RH Chen, CT ChienJournal of Neuroscience 32 (47), 16971-16981, 2012201
29
2012
Suppression of Hedgehog signaling by Cul3 ligases in proliferation control of retinal precursors
CY Ou, CH Wang, J Jiang, CT ChienDevelopmental biology 308 (1), 106-119, 2007200
29
2007

Referred From: https://scholar.google.com/citations?user=S9akhQ8AAAAJ&hl=en

Cited by
Citations 7284
h-index 32
i10-index 52
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