Author

Guohui Wan

Professor of Chemistry - Cited by 3,148 - compound development - chemistry modification

Biography

Dr Guohui Wan has received his PhD in Biochemistry at the Chinese University of Hong Kong in 2009. Currently, he is working as an Instructor at the University of Texas MD Anderson Cancer Center.  He received Trust Postdoctoral Fellowship Award and Best Poster Award etc. He is a member of the American Association for Cancer Research, the American Association for the Advancement of Science and the National Postdoctoral Association. 
Title
Cited by
Year
RNA N6-methyladenosine demethylase FTO promotes breast tumor progression through inhibiting BNIP3
Y Niu, Z Lin, A Wan, H Chen, H Liang, L Sun, Y Wang, X Li, X Xiong, ...Molecular cancer 18, 1-16, 2019201
398
2019
The ATM kinase induces microRNA biogenesis in the DNA damage response
X Zhang, G Wan, FG Berger, X He, X LuMolecular cell 41 (4), 371-383, 2011201
263
2011
RNA m6A methylation regulates sorafenib resistance in liver cancer through FOXO3‐mediated autophagy
Z Lin, Y Niu, A Wan, D Chen, H Liang, X Chen, L Sun, S Zhan, L Chen, ...The EMBO journal 39 (12), e103181, 2020202
236
2020
TP53 loss creates therapeutic vulnerability in colorectal cancer
Y Liu, X Zhang, C Han, G Wan, X Huang, C Ivan, D Jiang, ...Nature 520 (7549), 697-701, 2015201
226
2015
Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway
G Wan, R Mathur, X Hu, Y Liu, X Zhang, G Peng, X LuCellular signalling 25 (5), 1086-1095, 2013201
218
2013
miR-203 induces oxaliplatin resistance in colorectal cancer cells by negatively regulating ATM kinase
Y Zhou, G Wan, R Spizzo, C Ivan, R Mathur, X Hu, X Ye, J Lu, F Fan, L Xia, ...Molecular oncology 8 (1), 83-92, 2014201
177
2014
Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway
X Zhang, G Wan, S Mlotshwa, V Vance, FG Berger, H Chen, X LuCancer research 70 (18), 7-7186, 2010201
176
2010
miRNA response to DNA damage
G Wan, R Mathur, X Hu, X Zhang, X LuTrends in biochemical sciences 36 (9), 478-484, 2011201
168
2011
A novel non‐coding RNA lncRNA‐JADE connects DNA damage signalling to histone H4 acetylation
G Wan, X Hu, Y Liu, C Han, AK Sood, GA Calin, X Zhang, X LuThe EMBO journal 32 (21), 2833-2847, 2013201
137
2013
The RNA-binding protein DDX1 promotes primary microRNA maturation and inhibits ovarian tumor progression
C Han, Y Liu, G Wan, HJ Choi, L Zhao, C Ivan, X He, AK Sood, X Zhang, ...Cell reports 8 (5), 1447-1460, 2014201
102
2014
DNA-damage-induced nuclear export of precursor microRNAs is regulated by the ATM-AKT pathway
G Wan, X Zhang, RR Langley, Y Liu, X Hu, C Han, G Peng, LM Ellis, ...Cell reports 3 (6), 2100-2112, 2013201
78
2013
Amplification of USP13 drives ovarian cancer metabolism
C Han, L Yang, HH Choi, J Baddour, A Achreja, Y Liu, Y Li, J Li, G Wan, ...Nature communications 7 (1), 13525, 2016201
78
2016
N6-Methyladenosine modification: a novel pharmacological target for anti-cancer drug development
Y Niu, A Wan, Z Lin, X Lu, G WanActa pharmaceutica sinica B 8 (6), 833-843, 2018201
66
2018
RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer
L Sun, A Wan, Z Zhou, D Chen, H Liang, C Liu, S Yan, Y Niu, Z Lin, ...Gut 70 (9), 1698-1712, 2021202
49
2021
Noncoding RNAs in DNA repair and genome integrity
G Wan, Y Liu, C Han, X Zhang, X LuAntioxidants & Redox Signaling 20 (4), 655-677, 2014201
48
2014
MiR-137 regulates epithelial-mesenchymal transition in gastrointestinal stromal tumor
S Liu, J Cui, G Liao, Y Zhang, K Ye, T Lu, J Qi, G WanTumor Biology 35, 9131-9138, 2014201
46
2014
Loss‐of‐function genetic screening identifies aldolase a as an essential driver for liver cancer cell growth under hypoxia
Y Niu, Z Lin, A Wan, L Sun, S Yan, H Liang, S Zhan, D Chen, X Bu, P Liu, ...Hepatology 74 (3), 1461-1479, 2021202
41
2021
Tumor‐associated macrophages in immunotherapy
S Yan, G WanThe FEBS Journal 288 (21), 6174-6186, 2021202
36
2021
Crosstalk between the DNA damage response pathway and microRNAs
C Han, G Wan, RR Langley, X Zhang, X LuCellular and molecular life sciences 69, 2895-2906, 2012201
31
2012