Author

Kumiko Ui-Tei

The University of Tokyo - Cited by 6,985 - Genome information ncRNA siRNA therapy

Biography

 Dr Kumiko Ui-Tei is working as an Assistant Professor in the Department of Biological Sciences at the School of Science, The University of Tokyo, Japan. Her main interest is to elucidate the molecular basis of gene regulation by tiny protein-noncoding RNAs including short interfering RNAs (siRNAs) and microRNAs (miRNAs). Now, she researches the regulatory machinery of small RNAs on gene expression.
Title
Cited by
Year
CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites
Y Naito, K Hino, H Bono, K Ui-TeiBioinformatics 31 (7), 1120-1123, 2015201
955
2015
Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus
K Nishi, A Nishi, T Nagasawa, K Ui-TeiRna 19 (1), 17-35, 2013201
183
2013
Stability of miRNA 5′ terminal and seed regions is correlated with experimentally observed miRNA-mediated silencing efficacy
N Hibio, K Hino, E Shimizu, Y Nagata, K Ui-TeiScientific reports 2 (1), 996, 2012201
83
2012
siRNA design software for a target gene-specific RNA interference
Y Naito, K Ui-TeiFrontiers in genetics 3, 102, 2012201
76
2012
A-to-I editing in the miRNA seed region regulates target mRNA selection and silencing efficiency
H Kume, K Hino, J Galipon, K Ui-TeiNucleic acids research 42 (15), 10050-10060, 2014201
67
2014
The siRNA non-seed region and its target sequences are auxiliary determinants of off-target effects
PJ Kamola, Y Nakano, T Takahashi, PA Wilson, K Ui-TeiPLoS computational biology 11 (12), e1004656, 2015201
64
2015
Designing functional siRNA with reduced off-target effects
Y Naito, K Ui-TeisiRNA Design: Methods and Protocols, 57-68, 2013201
51
2013
Interactions between the non-seed region of siRNA and RNA-binding RLC/RISC proteins, Ago and TRBP, in mammalian cells
T Takahashi, S Zenno, O Ishibashi, T Takizawa, K Saigo, K Ui-TeiNucleic Acids Research 42 (8), 5256-5269, 2014201
47
2014
Differential binding of three major human ADAR isoforms to coding and long non-coding transcripts
J Galipon, R Ishii, Y Suzuki, M Tomita, K Ui-TeiGenes 8 (2), 68, 2017201
39
2017
LGP2 virus sensor regulates gene expression network mediated by TRBP-bound microRNAs
T Takahashi, Y Nakano, K Onomoto, F Murakami, C Komori, Y Suzuki, ...Nucleic acids research 46 (17), 9134-9147, 2018201
37
2018
Fc gamma receptor IIb participates in maternal IgG trafficking of human placental endothelial cells
T Ishikawa, T Takizawa, J Iwaki, T Mishima, K Ui-Tei, T Takeshita, ...International journal of molecular medicine 35 (5), 1273-1289, 2015201
36
2015
Control of the localization and function of a miRNA silencing component TNRC6A by Argonaute protein
K Nishi, T Takahashi, M Suzawa, T Miyakawa, T Nagasawa, Y Ming, ...Nucleic Acids Research 43 (20), 9856-9873, 2015201
36
2015
Thermodynamic control of small RNA-mediated gene silencing
K Ui-Tei, K Nishi, T Takahashi, T NagasawaFrontiers in genetics 3, 101, 2012201
34
2012
Optimal choice of functional and off-target effect-reduced siRNAs for RNAi therapeutics
K Ui-TeiFrontiers in Genetics 4, 107, 2013201
28
2013
Fluctuation of Rac1 activity is associated with the phenotypic and transcriptional heterogeneity of glioma cells
H Yukinaga, C Shionyu, E Hirata, K Ui-Tei, T Nagashima, S Kondo, ...Journal of cell science 1 (8), 1805-1815, 2014201
27
2014
Chemical modification of the siRNA seed region suppresses off-target effects by steric hindrance to base-pairing with targets
H Iribe, K Miyamoto, T Takahashi, Y Kobayashi, J Leo, M Aida, K Ui-TeiACS omega 2 (5), 2055-2064, 2017201
27
2017
Distinguishable in vitro binding mode of monomeric TRBP and dimeric PACT with siRNA
T Takahashi, T Miyakawa, S Zenno, K Nishi, M Tanokura, K Ui-TeiPloS one 8 (5), e63434, 2013201
25
2013
Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells
Deubiquitylase USP prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cellsN Shibata, N Ohoka, G Tsuji, Y Demizu, K Miyawaza, K Ui-Tei, T Akiyama, ...Oncogene 39 (19), 3867-3878, 2020202
25
2020
Extreme deformability of insect cell membranes is governed by phospholipid scrambling
A Shiomi, K Nagao, N Yokota, M Tsuchiya, U Kato, N Juni, Y Hara, ...Cell Reports 35 (10), 212
20
2021
Base-pairing probability in the microRNA stem region affects the binding and editing specificity of human A-to-I editing enzymes ADAR1-p110 and ADAR2
S Ishiguro, J Galipon, R Ishii, Y Suzuki, S Kondo, M Okada-Hatakeyama, ...RNA biology 15 (7), 976-989, 202
18
2018

Referred From: https://scholar.google.co.jp/citations?user=Ftg_jwQAAAAJ&hl=ja

Cited by
Citations 6985
h-index 37
i10-index 73
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