Author

Gaston K Mazandu

Division of Human Genetics, Department of Pathology, University of Cape (UCT) - Cited by 1,582 - Translational Bioinformatics and Epidemiology

Biography

Gaston K Mazandu, Computational Biology Group/Institute of Infectious Disease and Molecular Medicine, Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, South Africa. Skills and Expertise: Mycobacterium Tuberculosis, Functional Genomics, Bioinformatics and Computational Biology, Computational Biology, Protein-Protein Interaction, Pathway Analysis, Genome Sequencing, Computational Genomics, Biological Databases, Comparative Genomics.
Title
Cited by
Year
High-depth African genomes inform human migration and health
A Choudhury, S Aron, LR Botigué, D Sengupta, G Botha, T Bensellak, ...Nature 586 (7831), 741-748, 2020202
188
2020
Computational/in silico methods in drug target and lead prediction
FE Agamah, GK Mazandu, R Hassan, CD Bope, NE Thomford, ...Briefings in bioinformatics 21 (5), 1663-1675, 2020202
94
2020
A comprehensive survey of models for dissecting local ancestry deconvolution in human genome
E Geza, J Mugo, NJ Mulder, A Wonkam, ER Chimusa, GK MazanduBriefings in bioinformatics 20 (5), 1709-1724, 2019201
35
2019
Implementing artificial intelligence and digital health in resource-limited settings? Top 10 lessons we learned in congenital heart defects and cardiology
NE Thomford, CD Bope, FE Agamah, K Dzobo, R Owusu Ateko, ...Omics: a journal of integrative biology 24 (5), 264-277, 2020202
23
2020
Dissecting in silico Mutation Prediction of Variants in African Genomes: Challenges and Perspectives
CD Bope, ER Chimusa, V Nembaware, GK Mazandu, J De Vries, ...Frontiers in genetics 10, 601, 2019201
22
2019
Hydroxyurea-induced miRNA expression in sickle cell disease patients in Africa
K Mnika, GK Mazandu, M Jonas, GD Pule, ER Chimusa, NA Hanchard, ...Frontiers in genetics 10, 509, 191
20
2019
SickleInAfrica
J Makani, RZ Sangeda, O Nnodu, V Nembaware, A Osei-Akoto, V Paintsil, ...The Lancet Haematology 7 (2), e98-e99,
20
2020
A broad survey of DNA sequence data simulation tools
S Alosaimi, A Bandiang, N van Biljon, D Awany, PK Thami, MSS Tchamga, ...Briefings in functional genomics (1), 49-59, 2020202
19
2020
Post genome-wide association analysis: dissecting computational pathway/network-based approaches
ER Chimusa, S Dalvie, C Dandara, A Wonkam, GK MazanduBriefings in bioinformatics 20 (2), 690-700, 2019201
14
2019
Dating admixture events is unsolved problem in multi-way admixed populations
ER Chimusa, J Defo, PK Thami, D Awany, DD Mulisa, I Allali, H Ghazal, ...Briefings in Bioinformatics 21 (1), 144-155, 2020202
13
2020
Large-scale data-driven integrative framework for extracting essential targets and processes from disease-associated gene data sets
GK Mazandu, ER Chimusa, K Rutherford, EG Zekeng, ZZ Gebremariam, ...Briefings in bioinformatics 19 (6), 1141-1152, 2018201
12
2018
Establishing a multi-country sickle cell disease registry in Africa: ethical considerations
NS Munung, V Nembaware, J De Vries, D Bukini, F Tluway, M Treadwell, ...Frontiers in Genetics, 943, 2019201
12
2019
Establishing a sickle cell disease registry in Africa: experience from the Sickle Pan-African Research Consortium, Kumasi-Ghana
V Paintsil, EX Amuzu, I Nyanor, E Asafo-Adjei, AR Mohammed, ...Frontiers in Genetics 13, 802355, 2022202
11
2022
Identifying genetic variants and pathways associated with extreme levels of fetal hemoglobin in sickle cell disease in Tanzania
S Nkya, L Mwita, J Mgaya, H Kumburu, M van Zwetselaar, S Menzel, ...BMC Medical Genetics 21, 1-12, 2020202
10
2020
The hearing impairment ontology: A tool for unifying hearing impairment knowledge to enhance collaborative research
J Hotchkiss, N Manyisa, S Mawuli Adadey, OG Oluwole, E Wonkam, ...Genes 10 (12), 960, 2019201
8
2019
The sickle cell disease ontology: enabling collaborative research and co-designing of new planetary health applications
V Nembaware, GK Mazandu, J Hotchkiss, JM Safari Serufuri, J Kent, ...OMICS: A Journal of Integrative Biology 24 (10), 559-56, 2020202
7
2020
Plant genomics in Africa: present and prospects
H Ghazal, Y Adam, A Idrissi Azami, S Sehli, HN Nyarko, B Chaouni, ...The Plant Journal 10 (1), 21-36, 2021202
7
2021
Orienting future trends in local ancestry deconvolution models to optimally decipher admixed individual genome variations
GK Mazandu, E Geza, M Seuneu, ER ChimusaBioinformatics Tools for Detection and Clinical Interpretation of Genomic …, 2019201
5
2019
Designing data-driven learning algorithms: A necessity to ensure effective post-genomic medicine and biomedical research
GK Mazandu, I Kyomugisha, E Geza, M Seuneu, B Bah, ER ChimusaArtificial Intelligence-Applications in Medicine and Biology , 3-18, 2019201
5
2019