Author

Fritz Sorgel

Professor Pharmakologie - Cited by 11,328 - Antibiotika - Pharmakokinetik

Biography

Fritz Sorgel works as the Director, Institute of Biomedical and Pharmaceutical Research, Germany. he has written an editorial on Journal of Bioequivalence & Bioavailability. His current research is on Penetration of drugs through the blood-cerebrospinal fluid/blood-brain barrier for treatment of central nervous system infections  
Title
Cited by
Year
Ten years of biosimilars in Europe: development and evolution of the regulatory pathways
M Schiestl, M Zabransky, F SörgelDrug design, development and therapy, 1509-1515, 2017201
82
2017
The contamination of valsartan and other sartans, part 1: New findings
F Sörgel, M Kinzig, M Abdel-Tawab, C Bidmon, A Schreiber, S Ermel, ...Journal of pharmaceutical and biomedical analysis 172, 395-405, 2019201
55
2019
A systematic review of the stability of finished pharmaceutical products and drug substances beyond their labeled expiry dates
M Zilker, F Sörgel, U HolzgrabeJournal of pharmaceutical and biomedical analysis 166, 222-235, 2019201
44
2019
N-glycans of complex glycosylated biopharmaceuticals and their impact on protein clearance
F Higel, T Sandl, CY Kao, N Pechinger, F Sörgel, W Friess, F Wolschin, ...European Journal of Pharmaceutics and Biopharmaceutics 139, 123-131, 2019201
42
2019
Assessment of pharmacokinetic drug–drug interactions in humans: in vivo probe substrates for drug metabolism and drug transport revisited
U Fuhr, C Hsin, X Li, W Jabrane, F SörgelAnnual review of pharmacology and toxicology 59, 507-5, 2019201
36
2019
The contamination of valsartan and other sartans, Part 2: Untargeted screening reveals contamination with amides additionally to known nitrosamine impurities
O Scherf-Clavel, M Kinzig, A Besa, A Schreiber, C Bidmon, ...Journal of Pharmaceutical and Biomedical Analysis 172, 278-284, 2019201
35
2019
Pharmacokinetics of remdesivir in a COVID-19 patient with end-stage renal disease on intermittent haemodialysis
F Sörgel, JJ Malin, H Hagmann, M Kinzig, M Bilal, DA Eichenauer, ...Journal of Antimicrobial Chemotherapy 76 (3), 825-827, 2021202
35
2021
Regorafenib CSF penetration, efficacy, and MRI patterns in recurrent malignant glioma patients
PS Zeiner, M Kinzig, I Divé, GD Maurer, K Filipski, PN Harter, C Senft, ...Journal of Clinical Medicine 8 (12), 2031, 2019201
22
2019
Population modeling integrating pharmacokinetics, pharmacodynamics, pharmacogenetics, and clinical outcome in patients with sunitinib‐treated cancer
MH Diekstra, A Fritsch, F Kanefendt, JJ Swen, D Moes, F Sörgel, M Kinzig, ...CPT: pharmacometrics & systems pharmacology 6 (9), 604-613, 2017201
21
2017
A clinical drug‐drug interaction study assessing a novel drug transporter phenotyping cocktail with adefovir, sitagliptin, metformin, pitavastatin, and digoxin
C Trueck, C Hsin, O Scherf‐Clavel, E Schaeffeler, R Lenssen, M Gazzaz, ...Clinical pharmacology & therapeutics 106 (6), 1398-1407, 2019201
21
2019
Drinking ethanol has few acute effects on CYP2C9, CYP2C19, NAT2, and P‐glycoprotein activities but somewhat inhibits CYP1A2, CYP2D6, and intestinal CYP3A: so what?
M Gazzaz, M Kinzig, E Schaeffeler, M Jübner, C Hsin, X Li, M Taubert, ...Clinical Pharmacology & Therapeutics 104 (6), 1249-1259, 2018201
17
2018
Four decades of β-lactam antibiotic pharmacokinetics in cystic fibrosis
JB Bulitta, Y Jiao, SK Drescher, A Oliver, A Louie, B Moya, X Tao, ...Clinical Pharmacokinetics 58, 143-6, 2019201
15
2019
The nitrosamine contamination of drugs, part 3: Quantification of 4-Methyl-1-nitrosopiperazine in rifampicin capsules by LC-MS/HRMS
J Wohlfart, O Scherf-Clavel, M Kinzig, F Sörgel, U HolzgrabeJournal of Pharmaceutical and Biomedical Analysis 203, 114205, 2021202
13
2021
Sorafenib and everolimus in patients with advanced solid tumors and KRAS‐mutated NSCLC: a phase I trial with early pharmacodynamic FDG‐PET assessment
L Nogova, C Mattonet, M Scheffler, M Taubert, M Gardizi, ML Sos, ...Cancer Medicine 9 (14), 4991-5007, 2020202
12
2020
Pharmacokinetics and pharmacodynamics of antibiotics in bone
CB Landersdorfer, JB Bulitta, RL Nation, F SörgelBone and joint infections: from microbiology to diagnostics and treatment, 81-98, 2021202
11
2021
Novel population pharmacokinetic approach to explain the differences between cystic fibrosis patients and healthy volunteers via protein binding
NR Shah, JB Bulitta, M Kinzig, CB Landersdorfer, Y Jiao, DS Sutaria, ...Pharmaceutics (6), 286, 2019201
11
2019
Azathioprine-induced reversible EBV-associated Hodgkin-like lymphoma after immunosuppressive therapy for autoimmune hepatitis
M Munz, D Pretscher, M Wilhelm, U Holzgrabe, F Sörgel, J BirkmannInternational Journal of Clinical Pharmacology and Therapeutics 56 (3), 142, 2018201
10
2018
Isavuconazole therapeutic drug monitoring in critically ill ICU patients: a monocentric retrospective analysis
R Höhl, R Bertram, M Kinzig, GS Haarmeyer, M Baumgärtel, A Geise, ...Mycoses 65 (7), 747-752, 2022202
10
2022
A stability-study of expired ampoules manufactured more than 40 years ago
M Zilker, F Sörgel, U HolzgrabeJournal of Pharmaceutical and Biomedical Analysis 150, 318-326, 2018201
9
2018