Author

Mir A

Associate Director at Tessera Therapeutics - Cited by 1,349 - CRISPR - Genome Editing - Ribozymes - Structural Biology - Biochemistry

Biography

Mir A is working in the Rehman Medical Institute (RMI), Peshawar, Pakistan. The doctor's research interests are statistics, probability theory, hematology, blood disorders and transfusion medicine
Title
Cited by
Year
A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing
A Edraki, A Mir, R Ibraheim, I Gainetdinov, Y Yoon, CQ Song, Y Cao, ...Molecular cell 73 (4), 714-726. e4, 2019201
182
2019
Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice
P Liu, SQ Liang, C Zheng, E Mintzer, YG Zhao, K Ponnienselvan, A Mir, ...Nature communications 12 (1), 2121, 2021202
136
2021
NmeCas9 is an intrinsically high-fidelity genome-editing platform
N Amrani, XD Gao, P Liu, A Edraki, A Mir, R Ibraheim, A Gupta, KE Sasaki, ...Genome Biology 19 (1), 1-25, 2018201
109
2018
Potent Cas9 inhibition in bacterial and human cells by AcrIIC4 and AcrIIC5 anti-CRISPR proteins
J Lee, A Mir, A Edraki, B Garcia, N Amrani, HE Lou, I Gainetdinov, ...MBio 9 (6), e02321-18, 2018201
76
2018
Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo
R Ibraheim, PWL Tai, A Mir, N Javeed, J Wang, TC Rodríguez, ...Nature communications 12 (1), 6267, 2021202
38
2021
Nucleic acid-guided nucleases
J Kim, B Mijts, A Mir, A Garst, K SeamonUS Patent 10,704,033, 2020202
37
2020
Nucleic acid-guided nucleases
J Kim, B Mijts, A Mir, A Garst, K SeamonUS Patent 10,724,021, 2020202
37
2020
Nucleic acid-guided nucleases
J Kim, B Mijts, A Mir, A Garst, K SeamonUS Patent 10,745,678, 2020202
37
2020
Anti-CRISPR AcrIIA5 potently inhibits all Cas9 homologs used for genome editing
B Garcia, J Lee, A Edraki, Y Hidalgo-Reyes, S Erwood, A Mir, CN Trost, ...Cell reports 29 (7), 1739-1746. e5, 2019201
36
2019
Nucleic acid-guided nucleases
J Kim, B Mijts, A Mir, A Garst, K SeamonUS Patent 10,767,169, 2020202
29
2020
Efficient homology-directed repair with circular ssDNA donors
S Iyer, A Mir, J Vega-Badillo, BP Roscoe, R Ibraheim, LJ Zhu, J Lee, P Liu, ...bioRxiv, 864199, 2019201
12
2019
Automated multi-module cell processing methods, instruments, and systems
E Feldman, B Mijts, A Mir, E Zimmerman, A GarstUS Patent ,689,669, 2020202
10
2020
Engineered enzymes
B Mijts, J Kim, A Mir, K Seamon, A GarstUS Patent 10,655,114, 2020202
9
2020
Engineered enzymes
B Mijts, J Kim, A Mir, K Seamon, A GarstUS Patent 10,604,746, 2020202
8
2020
Engineered enzymes
B Mijts, J Kim, A Mir, K Seamon, A GarstUS Patent 10,640,754, 2020202
8
2020
Efficient homology-directed repair with circular single-stranded DNA donors
S Iyer, A Mir, J Vega-Badillo, BP Roscoe, R Ibraheim, LJ Zhu, J Lee, P Liu, ...The CRISPR Journal 5 (5), 85-701, 2022202
6
2022
Mad nucleases
B Mijts, J Kim, A Mir, A Garst, K SeamonUS Patent 10,883,095, 2021202
6
2021
Nucleic acid-guided nucleases
B Mijts, A Mir, A Garst, J Kim, K SeamonUS Patent 10,870,841, 2020202
5
2020
5
2021
Engineered enzymes
B Mijts, J Kim, A Mir, K Seamon, A GarstUS Patent 10,876,102, 2020202
5
2020