Author

Hazem Ghebeh

Scientist, King Faisal Specialist Hospital and Research Centre - Cited by 3,265 - Cancer stem cells - Stem cell immunology - Immunotherapy - Biomarker discovery

Biography

Dr. Hazem Ghebeh is an Associate professor in the Stem Cell & Tissue Re-engineering Program, King Faisal Specialist Hospital and Research Centre, Saudi Arabia. His study interests major on Stem Cell. In recent years, he has studied several on Cancer stem cells, Glioma, Melanoma, Epithelial-tomesenchymal-transition. Currently, Dr. Ghebeh  is the author/editors/reviewer in several international journals. He published 10 articles in many journals and the articles are informative and got good citations.
Title
Cited by
Year
Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule
H Ghebeh, C Lehe, E Barhoush, K Al-Romaih, A Tulbah, M Al-Alwan, ...Breast Cancer Research 12, 1-12, 2010201
239
2010
Bidirectional crosstalk between PD-L1 expression and epithelial to mesenchymal transition: significance in claudin-low breast cancer cells
A Alsuliman, D Colak, O Al-Harazi, H Fitwi, A Tulbah, T Al-Tweigeri, ...Molecular cancer 14, 1-13, 2015201
207
2015
PD‐L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation
S Almozyan, D Colak, F Mansour, A Alaiya, O Al‐Harazi, A Qattan, ...International journal of cancer 141 (7), 1402-1412, 2017201
177
2017
Fascin is a key regulator of breast cancer invasion that acts via the modification of metastasis-associated molecules
M Al-Alwan, S Olabi, H Ghebeh, E Barhoush, A Tulbah, T Al-Tweigeri, ...PloS one 6 (11), e27339, 2011201
116
2011
Profiling of normal and malignant breast tissue show CD44high/CD24lowphenotype as a predominant stem/progenitor marker when used in combination with Ep-CAM/CD49f markers
H Ghebeh, GM Sleiman, PS Manogaran, A Al-Mazrou, E Barhoush, ...BMC cancer 13 (1), 1-14, 2013201
84
2013
Fascin is involved in the chemotherapeutic resistance of breast cancer cells predominantly via the PI3K/Akt pathway
H Ghebeh, S Al-Khaldi, S Olabi, A Al-Dhfyan, F Al-Mohanna, R Barnawi, ...British journal of cancer 111 (8), 1552-1561, 2014201
75
2014
Fascin is critical for the maintenance of breast cancer stem cell pool predominantly via the activation of the notch self-renewal pathway
R Barnawi, S Al-Khaldi, G Majed Sleiman, A Sarkar, A Al-Dhfyan, ...Stem cells 34 (12), 2799-2813, 2016201
67
2016
Therapeutic targeting of B7-H1 in breast cancer
A Hasan, H Ghebeh, C Lehe, R Ahmad, S DermimeExpert opinion on therapeutic targets 15 (10), 1211-1225, 2011201
57
2011
Novel CARMIL2 mutations in patients with variable clinical dermatitis, infections, and combined immunodeficiency
AM Alazami, M Al-Helale, S Alhissi, B Al-Saud, H Alajlan, D Monies, ...Frontiers in Immunology 9, 203, 2018201
54
2018
Differential marker expression by cultures rich in mesenchymal stem cells
A Wetzig, A Alaiya, M Al-Alwan, CB Pradez, MS Pulicat, A Al-Mazrou, ...BMC cell biology 14, 1-12, 2013201
50
2013
PD-L1 is overexpressed on breast cancer stem cells through notch3/mTOR axis
FA Mansour, A Al-Mazrou, F Al-Mohanna, M Al-Alwan, H GhebehOncoimmunology 9 (1), 1729299, 2020202
46
2020
Metformin inhibits 7, 12-dimethylbenz [a] anthracene-induced breast carcinogenesis and adduct formation in human breast cells by inhibiting the cytochrome P4501A1/aryl …
ZH Maayah, H Ghebeh, AA Alhaider, AOS El-Kadi, AA Soshilov, ...Toxicology and applied pharmacology 284 (2), 217-226, 2015201
41
2015
Tocilizumab potentiates cisplatin cytotoxicity and targets cancer stem cells in triple‐negative breast cancer
NN Alraouji, FH Al‐Mohanna, H Ghebeh, M Arafah, R Almeer, ...Molecular Carcinogenesis, 2020202
40
2020
β1 Integrin is essential for fascin‐mediated breast cancer stem cell function and disease progression
R Barnawi, S Al‐Khaldi, D Colak, A Tulbah, T Al‐Tweigeri, M Fallatah, ...International Journal of Cancer 145 (3), 830-841, 2019201
34
2019
Complete response of chemo-refractory metastatic metaplastic breast cancer to paclitaxel-immunotherapy combination
AD Al Sayed, MA Elshenawy, A Tulbah, T Al-Tweigeri, H GhebehThe American Journal of Case Reports 20, 1630, 2019201
31
2019
Prevalence of PIK3CA mutations and the SNP rs17849079 in Arab breast cancer patients
B Karakas, D Colak, N Kaya, H Ghebeh, A Al-Qasem, F Hendrayani, ...Cancer biology & therapy 14 (10), 888-896, 2013201
31
2013
Senescent breast luminal cells promote carcinogenesis through interleukin-8-dependent activation of stromal fibroblasts
HH Al-Khalaf, H Ghebeh, R Inass, A AboussekhraMolecular and cellular biology 39 (2), e00359-18, 2019201
27
2019
Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking
LE Sanderson, K Lanko, M Alsagob, R Almass, N Al-Ahmadi, M Najafi, ...Brain 144 (3), 769-780, 2021202
27
2021
Fascin activates β-catenin signaling and promotes breast cancer stem cell function mainly through focal adhesion kinase (FAK): relation with disease progression
R Barnawi, S Al-Khaldi, T Bakheet, M Fallatah, A Alaiya, H Ghebeh, ...Frontiers in Oncology 10, 440, 2020202
23
2020
CD3+ T-lymphocyte infiltration is an independent prognostic factor for advanced nasopharyngeal carcinoma
N Al-Rajhi, H Soudy, SA Ahmed, T Elhassan, SF Mohammed, HA Khoja, ...BMC cancer 20, 1-13, 2020202
19
2020

Referred From: https://scholar.google.com/citations?hl=en&user=pzI9wRQAAAAJ

Cited by
Citations 3265
h-index 26
i10-index 36
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