Author

Alejandro BC

Institut Pasteur de Montevideo - Cited by 4,871 - Structural Biology - Microbiology - signaling - regulation - allostery

Biography

Alejandro Buschiazzo is at Institut Pasteur De Montevideo in Paris, France. His top areas of expertise are Leptospirosis, Chagas Disease, Chronic B-Cell Leukemia, and Chronic Lymphocytic Leukemia.
Title
Cited by
Year
What Makes a Bacterial Species Pathogenic?: Comparative Genomic Analysis of the Genus Leptospira
DE Fouts, MA Matthias, H Adhikarla, B Adler, L Amorim-Santos, DE Berg, ...PLOS Negl Trop Dis 10 (2), e0004403, 2016201
275
2016
Data publication with the structural biology data grid supports live analysis
PA Meyer, S Socias, J Key, E Ransey, EC Tjon, A Buschiazzo, M Lei, ...Nature Communications 7, 10882, 2016201
101
2016
Two-component sensing and regulation: How do histidine kinases talk with response regulators at the molecular level?
A Buschiazzo, F TrajtenbergAnnual review of microbiology 73, 507-528, 2019201
90
2019
A novel flagellar sheath protein, FcpA, determines filament coiling, translational motility and virulence for the Leptospira spirochete
EA Wunder Jr, CP Figueira, N Benaroudj, B Hu, BA Tong, F Trajtenberg, ...Molecular microbiology 101 (3), 457-470, 2016201
78
2016
Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis
L Zarantonelli, A Suanes, P Meny, F Buroni, C Nieves, X Salaberry, ...PLoS neglected tropical diseases 12 (9), e0006694, 2018201
59
2018
Structural and Molecular Basis of the Peroxynitrite-mediated Nitration and Inactivation of Trypanosoma cruzi Iron-Superoxide Dismutases (Fe-SODs) A and B DISPARATE …
A Martinez, G Peluffo, AA Petruk, M Hugo, D Piñeyro, V Demicheli, ...Journal of Biological Chemistry 289 (18), 12760-12778, 2014201
59
2014
Regulation of signaling directionality revealed by 3D snapshots of a kinase: regulator complex in action
F Trajtenberg, JA Imelio, MR Machado, N Larrieux, MA Marti, G Obal, ...eLife 5, e21422, 2016201
58
2016
Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation
F Trajtenberg, D Albanesi, N Ruétalo, H Botti, AE Mechaly, M Nieves, ...mBio 5 (6), e02105-14, 2014201
55
2014
A coiled coil switch mediates cold sensing by the thermosensory protein DesK
E Saita, LA Abriata, YT Tsai, F Trajtenberg, T Lemmin, A Buschiazzo, ...Molecular microbiology 98 (2), 258-271, 2015201
54
2015
Trypanosoma cruzi trans-sialidase in complex with a neutralizing antibody: structure/function studies towards the rational design of inhibitors
A Buschiazzo, R Muiá, N Larrieux, T Pitcovsky, J Mucci, O CampetellaPLoS Pathog 8 (1), e1002474, 2012201
51
2012
Consecutive interactions with HSP90 and eEF1A underlie a functional maturation and storage pathway of AID in the cytoplasm
SP Methot, LC Litzler, F Trajtenberg, A Zahn, F Robert, J Pelletier, ...Journal of Experimental Medicine 212 (4), 581-596, 2015201
48
2015
Conformational plasticity of a native retroviral capsid revealed by x-ray crystallography
G Obal, F Trajtenberg, F Carrión, L Tomé, N Larrieux, X Zhang, O Pritsch, ...Science 349 (6243), 95-98, 2015201
44
2015
Crystal Structure of the Metallo-β-Lactamase GOB in the Periplasmic Dizinc Form Reveals an Unusual Metal Site
J Morán-Barrio, MN Lisa, N Larrieux, SI Drusin, AM Viale, DM Moreno, ...Antimicrobial Agents and Chemotherapy 60 (10), 6013-6022, 2016201
42
2016
39
2010
Structural insights into bacterial resistance to cerulenin
F Trajtenberg, S Altabe, N Larrieux, F Ficarra, D de Mendoza, ...The FEBS journal 281 (10), 2324-23, 2014201
38
2014
Structural basis for feed-forward transcriptional regulation of membrane lipid homeostasis in Staphylococcus aureus
D Albanesi, G Reh, ME Guerin, F Schaeffer, M Debarbouille, ...PLoS Pathog 9 (1), e1003108, 2013201
36
2013
Structural coupling between autokinase and phosphotransferase reactions in a bacterial histidine kinase
AE Mechaly, SS Diaz, N Sassoon, A Buschiazzo, JM Betton, PM AlzariStructure 25 (6), 939-944. e3, 2017201
34
2017
SIMBAD: a sequence‐independent molecular‐replacement pipeline
AJ Simpkin, F Simkovic, JMH Thomas, M Savko, A Lebedev, V Uski, ...Acta Crystallographica Section D 74 (7), 595-605, 2018201
29
2018
Structure of a human IgA1 Fab fragment at 1.55 A resolution: potential effect of the constant domains on antigen-affinity modulation
A Correa, F Trajtenberg, G Obal, O Pritsch, G Dighiero, P Oppezzo, ...Acta Crystallographica Section D: Biological Crystallography 69 (3), 388-397, 2013201
29
2013
Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis
A East, AE Mechaly, GHM Huysmans, C Bernarde, D Tello-Manigne, ...Structure 24 (1), 92-104, 2016201
28
2016