Author

Cheng-Chang Tsai

Director of Business Development, XtalPi Inc. - Cited by 541 - Computer-aided drug design - CpHMD - Data science - Machine learning

Biography

Cheng-Chang Tsai is currently working as a Director of Business Development, XtalPi Inc; he extended his valuable service in field of Pharmacology and Toxicology for several years and has been a recipient of few awards and grants. His research interests reflect in his wide range of publications in various national and international journals.
Title
Cited by
Year
Comparison of radii sets, entropy, QM methods, and sampling on MM‐PBSA, MM‐GBSA, and QM/MM‐GBSA ligand binding energies of F. tularensis enoyl‐ACP …
PC Su, CC Tsai, S Mehboob, KE Hevener, ME JohnsonJournal of computational chemistry 36 (25), 1859-1873, 2015201
104
2015
Assessing lysine and cysteine reactivities for designing targeted covalent kinase inhibitors
R Liu, Z Yue, CC Tsai, J ShenJournal of the American Chemical Society 141 (16), 6553-6560, 2019201
75
2019
Constant pH molecular dynamics reveals pH-modulated binding of two small-molecule BACE1 inhibitors
CR Ellis, CC Tsai, X Hou, J ShenThe journal of physical chemistry letters 7 (6), 944-949, 2016201
50
2016
Electrical programming of soft matter: Using temporally varying electrical inputs to spatially control self assembly
K Yan, Y Liu, J Zhang, SO Correa, W Shang, CC Tsai, WE Bentley, J Shen, ...Biomacromolecules 19 (2), 364-373, 2018201
45
2018
Electrical writing onto a dynamically responsive polysaccharide medium: patterning structure and function into a reconfigurable medium
S Wu, K Yan, Y Zhao, CC Tsai, J Shen, WE Bentley, Y Chen, H Deng, ...Advanced Functional Materials 28 (40), 1803139, 2018201
34
2018
Predicting catalytic proton donors and nucleophiles in enzymes: How adding dynamics helps elucidate the structure–function relationships
Y Huang, Z Yue, CC Tsai, JA Henderson, J ShenThe journal of physical chemistry letters 9 (6), 1179-1184, 2018201
34
2018
Proton-coupled conformational allostery modulates the inhibitor selectivity for β-secretase
RC Harris, CC Tsai, CR Ellis, J ShenThe journal of physical chemistry letters 8 (19), 4832-4837, 2017201
34
2017
Toward understanding the environmental control of hydrogel film properties: how salt modulates the flexibility of chitosan chains
CC Tsai, BH Morrow, W Chen, GF Payne, J ShenMacromolecules 50 (15), 5946-5952, 2017201
33
2017
Conformational dynamics of cathepsin D and binding to a small‐molecule BACE1 inhibitor
CR Ellis, CC Tsai, FY Lin, J ShenJournal of computational chemistry 38 (15), 1260-1269, 2017201
27
2017
How electrostatic coupling enables conformational plasticity in a tyrosine kinase
CC Tsai, Z Yue, J ShenJournal of the American Chemical Society 141 (38), 15092-15101, 2019201
24
2019
How ligand protonation state controls water in protein–ligand binding
JA Henderson, RC Harris, CC Tsai, J ShenThe journal of physical chemistry letters 9 (18), 5440-5444, 2018201
24
2018
Trowaglerix venom polypeptides as a novel antithrombotic agent by targeting immunoglobulin-like domains of glycoprotein VI in platelet
CH Chang, CH Chung, YS Tu, CC Tsai, CC Hsu, HC Peng, YJ Tseng, ...Arteriosclerosis, Thrombosis, and Vascular Biology 37 (7), 1307-1314, 2017201
24
2017
Exploring pH-responsive, switchable crosslinking mechanisms for programming reconfigurable hydrogels based on aminopolysaccharides
CC Tsai, GF Payne, J ShenChemistry of Materials 30 (23), 8597-8605, 2018201
22
2018
Polyelectrolyte in Electric Field: Disparate Conformational Behavior along an Aminopolysaccharide Chain
P Mahinthichaichan, CC Tsai, GF Payne, J ShenACS omega 5 (21), 12016-12026, 2020202
10
2020
A Proof-of-Concept Inhibitor of Endothelial Lipase Suppresses Triple-Negative Breast Cancer Cells by Hijacking the Mitochondrial Function
R Yang, S Han, J Clayton, M Haghighatian, CC Tsai, Y Yao, P Li, J Shen, ...Cancers 4 (5), 3763, 2022202
1
2022

Referred From: https://scholar.google.com/citations?user=4VT2MFUAAAAJ&hl=en

Cited by
Citations 541
h-index 13
i10-index 14
Recommended Journals
Open Access Journals