Author

Jacklyn N. Hellwege

Research Assistant Professor, Division of Genetic Medicine, Vanderbilt University Medical Center - Cited by 3,038 - genetic epidemiology

Biography

She is affiliated to Wake Forest School of Medicine, Winston-Salem, North Carolina, USA, She is a recipient of many awards and grants for her valuable contributions and discoveries in the major areas of Molecular Genetics and Genomics research. Her international experience includes various programs, contributions and participation in different countries for diverse fields of study. Her research interests reflect in her wide range of publications in various national and international journals
Title
Cited by
Year
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
P Surendran, EV Feofanova, N Lahrouchi, I Ntalla, S Karthikeyan, J Cook, ...Nature genetics 52 (12), 1314-1332, 2020202
82
2020
Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments
X Sheng, Y Guan, Z Ma, J Wu, H Liu, C Qiu, S Vitale, Z Miao, MJ Seasock, ...Nature genetics 53 (9), 1322-1333, 2021202
63
2021
Relationship between blood pressure and incident cardiovascular disease: linear and nonlinear mendelian randomization analyses
R Malik, MK Georgakis, M Vujkovic, SM Damrauer, P Elliott, V Karhunen, ...Hypertension 77 (6), 2004-2013, 2021202
39
2021
A single genetic locus controls both expression of DPEP1/CHMP1A and kidney disease development via ferroptosis
Y Guan, X Liang, Z Ma, H Hu, H Liu, Z Miao, A Linkermann, JN Hellwege, ...Nature communications 12 (1), 5078, 2021202
32
2021
Genome-wide polygenic score to predict chronic kidney disease across ancestries
A Khan, MC Turchin, A Patki, V Srinivasasainagendra, N Shang, ...Nature medicine 28 (7), 1412-1420, 2022202
24
2022
Lessons learned from the eMERGE Network: balancing genomics in discovery and practice
eMERGE ConsortiumHuman Genetics and Genomics Advances 2 (1), 100018, 2021202
17
2021
Association between genetic variation in blood pressure and increased lifetime risk of peripheral artery disease
MG Levin, D Klarin, VM Walker, D Gill, J Lynch, JN Hellwege, JM Keaton, ...Arteriosclerosis, thrombosis, and vascular biology 41 (6), 2027-2034, 2021202
14
2021
The polygenic architecture of left ventricular mass mirrors the clinical epidemiology
JD Mosley, RT Levinson, E Farber-Eger, TL Edwards, JN Hellwege, ...Scientific reports 10 (1), 7561, 2020202
12
2020
Genome-wide association study of apparent treatment-resistant hypertension in the CHARGE consortium: the CHARGE pharmacogenetics working group
MR Irvin, CM Sitlani, JS Floyd, BM Psaty, JC Bis, KL Wiggins, EA Whitsel, ...American Journal of Hypertension 32 (12), 46-53, 2019201
11
2019
Returning integrated genomic risk and clinical recommendations: The eMERGE study
JE Linder, A Allworth, ST Bland, PJ Caraballo, RL Chisholm, EW Clayton, ...Genetics in Medicine 25 (4), 100006, 2023202
9
2023
Evidence that geographic variation in genetic ancestry associates with uterine fibroids
JM Keaton, EA Jasper, JN Hellwege, SH Jones, ES Torstenson, ...Human genetics 140, 1433-1440, 2021202
7
2021
Genetic thyrotropin regulation of atrial fibrillation risk is mediated through an effect on height
M Shi, AM Manouchehri, CM Shaffer, NS Vaitinadin, JN Hellwege, ...The Journal of Clinical Endocrinology & Metabolism 106 (7), 2124-2132, 2021202
5
2021
Insights from a large-scale whole-genome sequencing study of systolic blood pressure, diastolic blood pressure, and hypertension
TN Kelly, X Sun, KY He, MR Brown, SAG Taliun, JN Hellwege, MR Irvin, ...Hypertension 79 (8), 1656-1667, 2022202
4
2022
Blood pressure polygenic scores are associated with apparent treatment-resistant hypertension
JH Breeyear, MM Shuey, TL Edwards, JN HellwegeCirculation. Genomic and precision medicine 15 (), e00554, 2022202
3
2022
Blunted PTH response to vitamin D insufficiency/deficiency and colorectal neoplasia risk
JN Hellwege, X Zhu, X Huang, MJ Shrubsole, L Fan, B Li, R Ness, ...Clinical Nutrition 40 (5), 05-1, 2021202
3
2021
Uterine fibroid polygenic risk score (PRS) associates and predicts risk for uterine fibroid
JA Piekos, JN Hellwege, Y Zhang, ES Torstenson, GP Jarvik, O Dikilitas, ...Human genetics 141 (11), 1739-1748, 0
2
2022
Whole genome sequence analysis of blood pressure phenotypes in the trans-omics for precision medicine and centers for common disease genomics programs
TN Kelly, X Sun, JA Brody, SA Gagliano, KY He, JN Hellwege, ...Circulation 141 (Suppl_1), A46-A46, 000
2
2020
Genetic correlations and exploration of uterine fibroid clinical phenome in black and white women
BS Mautz, SH Jones, ES Torstenson, JN Hellwege, TL Edwards, ...Genetic Epidemiology 43 (7), 897-897, 20920
1
2019
Association of apparent treatment-resistant hypertension with differential risk of end-stage kidney disease across racial groups in the million veteran program
EA Akwo, C Robinson-Cohen, CP Chung, SC Shah, NJ Brown, TA Ikizler, ...Hypertension 78 (2), 376-386, 20220
1
2021