Author

M Pinto

university of miami - Cited by 2,256 - mitochondrial diseases - neurodegenerative diseases

Biography

Department of Chemical and Environmental Engineering, Universidad Técnica Federico Santa María, P.O. Box 110-V, Valparaíso, Chile Department of Chemical and Environmental Engineering, Universidad Técnica Federico Santa María, P.O. Box 110-V, Valparaíso, Chile
Title
Cited by
Year
Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs
SR Bacman, SL Williams, M Pinto, S Peralta, CT MoraesNature medicine 19 (9), 1111-1113, 2013201
436
2013
Unexpected expression of α-and β-globin in mesencephalic dopaminergic neurons and glial cells
M Biagioli, M Pinto, D Cesselli, M Zaninello, D Lazarevic, P Roncaglia, ...Proceedings of the National Academy of Sciences 106 (36), 15454-15459, 2009200
299
2009
MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation
SR Bacman, JHK Kauppila, CV Pereira, N Nissanka, M Miranda, M Pinto, ...Nature medicine 24 (11), 1696-1700, 2018201
205
2018
Mechanisms linking mtDNA damage and aging
M Pinto, CT MoraesFree Radical Biology and Medicine 85, 250-258, 2015201
194
2015
The striatum is highly susceptible to mitochondrial oxidative phosphorylation dysfunctions
AM Pickrell, H Fukui, X Wang, M Pinto, CT MoraesJournal of neuroscience 31 (27), 9895-9904, 2011201
112
2011
Mitochondrial genome changes and neurodegenerative diseases
M Pinto, CT MoraesBiochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (8 …, 2014201
87
2014
Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation
S Zucchelli, F Marcuzzi, M Codrich, E Agostoni, S Vilotti, M Biagioli, ...Journal of Biological Chemistry 286 (28), 25108-25117, 2011201
69
2011
Pioglitazone ameliorates the phenotype of a novel Parkinson’s disease mouse model by reducing neuroinflammation
M Pinto, N Nissanka, S Peralta, R Brambilla, F Diaz, CT MoraesMolecular neurodegeneration 11 (1), 1-15, 2016201
65
2016
Cryptic Amyloidogenic elements in the 3′ UTRs of Neurofilament genes trigger axonal neuropathy
AP Rebelo, AJ Abrams, E Cottenie, A Horga, M Gonzalez, DM Bis, ...The American Journal of Human Genetics 98 (4), 597-614, 2016201
55
2016
Transient mitochondrial DNA double strand breaks in mice cause accelerated aging phenotypes in a ROS-dependent but p53/p21-independent manner
M Pinto, AM Pickrell, X Wang, SR Bacman, A Yu, A Hida, LM Dillon, ...Cell Death & Differentiation 24 (2), 288-299, 2017201
52
2017
The use of mitochondria-targeted endonucleases to manipulate mtDNA
SR Bacman, SL Williams, M Pinto, CT MoraesMethods in enzymology 547, 373-397, 2014201
50
2014
Transient systemic mtDNA damage leads to muscle wasting by reducing the satellite cell pool
X Wang, AM Pickrell, SG Rossi, M Pinto, LM Dillon, A Hida, RL Rotundo, ...Human molecular genetics 22 (19), 3976-3986, 2013201
50
2013
Mitochondrial DNA double-strand breaks in oligodendrocytes cause demyelination, axonal injury, and CNS inflammation
PM Madsen, M Pinto, S Patel, S McCarthy, H Gao, M Taherian, S Karmally, ...Journal of Neuroscience 37 (42), 10185-10199, 2017201
33
2017
Regional susceptibilities to mitochondrial dysfunctions in the CNS
M Pinto, AM Pickrell, CT MoraesWalter de Gruyter 393 (4), 275-281, 2012201
23
2012
Metformin delays neurological symptom onset in a mouse model of neuronal complex I deficiency
S Peralta, M Pinto, T Arguello, S Garcia, F Diaz, CT MoraesJCI insight 5 (21), 2020202
11
2020
Ablation of Cytochrome c in Adult Forebrain Neurons Impairs Oxidative Phosphorylation Without Detectable Apoptosis
M Pinto, UD Vempati, F Diaz, S Peralta, CT MoraesMolecular neurobiology 56, 322-335, 2019201
7
2019
Treatment with ROS detoxifying gold quantum clusters alleviates the functional decline in a mouse model of Friedreich ataxia
C Villa, M Legato, A Umbach, C Riganti, R Jones, B Martini, M Boido, ...Science translational medicine 13 (607), eabe1633, 2021202
5
2021
Image-based analysis of mitochondrial area and counting from adult mouse dopaminergic neurites
N Nissanka, CT Moraes, M PintoBio-protocol 8 (16), e2471-e2471, 2018201
3
2018
Adult-onset deficiency of mitochondrial complex III in a mouse model of Alzheimer’s disease decreases amyloid beta plaque formation
M Pinto, F Diaz, N Nissanka, CS Guastucci, P Illiano, R Brambilla, ...Molecular neurobiology 59 (10), 655-6566, 0
2
2022
Human Nmnat1 Promotes Autophagic Clearance of Amyloid Plaques in a Drosophila Model of Alzheimer’s Disease
Y Zhu, AG Lobato, RG Zhai, M PintoFrontiers in aging neuroscience 14, 8597, 0
2
2022