Author

Christopher B. Arena

Virginia Tech - Cited by 2,773 - Biomedical Engineering

Biography

Dr. Christopher received a B.S. degree from the University of Virginia and the Ph.D. degree from Virginia Tech, both in Biomedical Engineering. As a graduate student, he developed a new technology for non-thermal tissue ablation called high-frequency irreversible electroporation. He was an NIH IRACDA postdoctoral fellow at the University of North Carolina at Chapel Hill, where he worked on new diagnostic and therapeutic ultrasound techniques, including the use of phase change contrast agents.He has experience with commercializing medical devices in the field of bioelectricity.
Title
Cited by
Year
Selective modulation of intracellular effects of cells using pulsed electric fields
MB Sano, B Christopher, SS Verbridge, RV DavalosUS Patent 10,471,254, 2019201
190
2019
Contrast-enhanced ultrasound imaging and in vivo circulatory kinetics with low-boiling-point nanoscale phase-change perfluorocarbon agents
PS Sheeran, JD Rojas, C Puett, J Hjelmquist, CB Arena, PA DaytonUltrasound in medicine & biology 41 (3), 814-831, 2015201
121
2015
Mitigation of impedance changes due to electroporation therapy using bursts of high-frequency bipolar pulses
SP Bhonsle, CB Arena, DC Sweeney, RV DavalosBiomedical engineering online 14 (3), 1-14, 2015201
109
2015
Bursts of bipolar microsecond pulses inhibit tumor growth
MB Sano, CB Arena, KR Bittleman, MR DeWitt, HJ Cho, CS Szot, D Saur, ...Scientific reports 5 (1), 14999, 2015201
105
2015
Treatment planning for electrical-energy based therapies based on cell characteristics
RV Davalos, B ChristopherUS Patent App. 14/686,380, 2015201
73
2015
High-frequency irreversible electroporation for intracranial meningioma: a feasibility study in a spontaneous canine tumor model
EL Latouche, CB Arena, JW Ivey, PA Garcia, TE Pancotto, N Pavlisko, ...Technology in cancer research & treatment 17, 1533033818785285, 2018201
63
2018
System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
PA Garcia, B Christopher, MB Sano, RV DavalosUS Patent 10,117,707, 2018201
60
2018
Avoiding nerve stimulation in irreversible electroporation: a numerical modeling study
B Mercadal, CB Arena, RV Davalos, A IvorraPhysics in Medicine & Biology 62 (20), 8060, 2017201
56
2017
Focused ultrasound-facilitated brain drug delivery using optimized nanodroplets: vaporization efficiency dictates large molecular delivery
SY Wu, SM Fix, CB Arena, CC Chen, W Zheng, OO Olumolade, ...Physics in Medicine & Biology 63 (3), 035002, 2018201
49
2018
An evaluation of the sonoporation potential of low-boiling point phase-change ultrasound contrast agents in vitro
SM Fix, A Novell, Y Yun, PA Dayton, CB ArenaJournal of therapeutic ultrasound 5, 1-11, 2017201
41
2017
High-frequency electroporation for cancer therapy
MB Sano, B Christopher, SS Verbridge, RV DavalosUS Patent App. 16/443,351, 2019201
31
2019
Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
B Christopher, RV Davalos, MB SanoUS Patent 11,382,681, 2022202
31
2022
Folate conjugated cellulose nanocrystals potentiate irreversible electroporation-induced cytotoxicity for the selective treatment of cancer cells
KR Colacino, CB Arena, S Dong, M Roman, RV Davalos, YW LeeTechnology in cancer research & treatment 14 (6), 757-766, 2015201
29
2015
Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
RV Davalos, M Bonakdar, EL Latouche, RL Mahajan, JL Robertson, ...US Patent 10,694,972, 2020202
29
2020
Targeted transthoracic acoustic activation of systemically administered nanodroplets to detect myocardial perfusion abnormalities
TR Porter, C Arena, S Sayyed, J Lof, RR High, F Xie, PA DaytonCirculation: Cardiovascular Imaging 9 (1), e003770, 2016201
28
2016
An evaluation of irreversible electroporation thresholds in human prostate cancer and potential correlations to physiological measurements
S Campelo, M Valerio, HU Ahmed, Y Hu, SL Arena, RE Neal, M Emberton, ...APL bioengineering 1 (1), 2017201
25
2017
Dual-frequency acoustic droplet vaporization detection for medical imaging
CB Arena, A Novell, PS Sheeran, C Puett, LC Moyer, PA DaytonIEEE transactions on ultrasonics, ferroelectrics, and frequency control 62 …, 151
20
2015
Rapid impedance spectroscopy for monitoring tissue impedance, temperature, and treatment outcome during electroporation-based therapies
MF Lorenzo, SP Bhonsle, CB Arena, RV DavalosIEEE Transactions on Biomedical Engineering 68 (5), 1536-1546, 2020202
18
2020
System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
PA Garcia, B Christopher, MB Sano, RV DavalosUS Patent 11,272,979, 2022202
18
2022
Selective modulation of intracellular effects of cells using pulsed electric fields
MB Sano, B Christopher, SS Verbridge, RV DavalosUS Patent 11,406,820, 2022202
16
2022

Referred From: https://scholar.google.com/citations?user=08quVwMAAAAJ&hl=en

Cited by
Citations 2773
h-index 28
i10-index 40
Recommended Journals
Open Access Journals