Author

Guacyara Da Motta

Professora Associada, Departamento de Bioqu

Biography

Associate Professor at the Department of Biochemistry at Federal University of São Paulo and was Coordinator of the Biological Sciences Course in Medical Modality (Biomedicine) at EPM/UNIFESP in the period 2008-2012. Coordinated the Structuring Faculty Nucleus of the Biomedicine Course at EPM/UNIFESP between 2011-2017. Has experience in Biochemistry, with emphasis on Protein Chemistry, Intermediate Metabolism and Cell Biology. The research area in which he works is mainly focused on the subject that studies the proteins of the plasma kallikrein-kinin system etc.
Title
Cited by
Year
High molecular weight kininogen regulates prekallikrein assembly and activation on endothelial cells: a novel mechanism for contact activation
G Motta, R Rojkjaer, AAK Hasan, DB Cines, AH SchmaierBlood, The Journal of the American Society of Hematology 91 (2), 516-528, 1998199
217
1998
Factor XII does not initiate prekallikrein activation on endothelial cells
R Røjkjær, AAK Hasan, G Motta, I Schousboe, AH SchmaierThrombosis and haemostasis 80 (07), 74-81, 1998199
104
1998
100
2003
Identification of prolylcarboxypeptidase as the cell matrix-associated prekallikrein activator
CR Moreira, AH Schmaier, F Mahdi, G da Motta, HB Nader, ...FEBS letters 523 (1-3), 167-170, 2002200
69
2002
Assembly of high molecular weight kininogen and activation of prekallikrein on cell matrix
G Motta, Z Shariat-Madar, F Mahdi, CAM Sampaio, AH SchmaierThrombosis and haemostasis 86 (09), 840-847, 2001200
55
2001
Effect of plant neutrophil elastase inhibitor on leucocyte migration, adhesion and cytokine release in inflammatory conditions
C Oliveira, RA Navarro‐Xavier, EA Anjos‐Vallota, JO Martins, ...British journal of pharmacology 161 (4), 899-910, 2010201
55
2010
PI class metalloproteinase from Bothrops moojeni venom is a post-proline cleaving peptidase with kininogenase activity: Insights into substrate selectivity and kinetic behavior
DN Okamoto, MY Kondo, LCG Oliveira, RV Honorato, LM Zanphorlin, ...Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (3), 545-552, 2014201
25
2014
Releasing or expression modulating mediator involved in hemostasis by Berythractivase and Jararhagin (SVMPs)
ALM Pereira, M Fritzen, F Faria, G Da Motta, AM Chudzinski-TavassiToxicon 47 (7), 788-796, 2006200
22
2006
Action of plant proteinase inhibitors on enzymes of the kallikrein kinin system.
CA Sampaio, G Motta, MU Sampaio, ML Oliva, MS Araujo, RC Stella, ...Agents and actions. Supplements 36, 191-199, 1992199
18
1992
Mycoplasma hyopneumoniae in vitro peptidase activities: identification and cleavage of kallikrein-kinin system-like substrates
L Moitinho-Silva, MY Kondo, LCG Oliveira, DN Okamoto, JA Paes, ...Veterinary microbiology 163 (3-4), 264-273, 2013201
17
2013
Plasma prekallikrein/kallikrein processing by lysosomal cysteine proteases
NMT Barros, L Puzer, ILS Tersariol, MLV Oliva, CAM Sampaio, ...Walter de Gruyter 385 (11), 1087-1091, 2004200
17
2004
High molecular weight kininogen as substrate for cathepsin B
NMT Barros, ILS Tersariol, MLV Oliva, MS Araújo, CAM Sampaio, ...Walter de Gruyter 385 (6), 551-555, 2004200
17
2004
14
2017
Involvement of heparan sulfate proteoglycans in cellular uptake of high molecular weight kininogen
KRB Melo, A Gutierrez, FD Nascimento, MS Araujo, MU Sampaio, ...Biological Chemistry 390 (2), 145-155, 2009200
13
2009
Bradykinin Release Avoids High Molecular Weight Kininogen Endocytosis
IZ Damasceno, KRB Melo, FD Nascimento, DSP Souza, MS Araujo, ...PLoS One 10, (3)e01721, 2015201
12
2015
Heparin affects the interaction of kininogen on endothelial cells
AJ Gozzo, G Motta, I Cruz-Silva, VA Nunes, NMT Barros, AK Carmona, ...Biochimie 93 (10), 1839-1845, 202
11
2011
The involvement of proteoglycans in the human plasma prekallikrein interaction with the cell surface
CL Veronez, FD Nascimento, KRB Melo, HB Nader, ILS Tersariol, G MottaPLoS One 9 (3), e91280, 2014201
10
2014
Plasma kallikrein‐kinin system contributes to peripheral inflammation in temporal lobe epilepsy
PSR Simoes, AO Zanelatto, MC Assis, PPV Varella, EM Yacubian, ...Journal of Neurochemistry 150 (3), 296-311, 2019201
10
2019
Hydrolysis of synthetic peptides and natural substrates by plasma kallikrein and its light chain.
G Motta, MU Sampaio, CA SampaioAdvances in Experimental Medicine and Biology 247, 239-242, 1989198
6
1989