Author

Peijuan Lu

Westlake University - Cited by 2,576 - Protein design

Biography

Peijuan Lu is affiliated to McColl-Lockwood Laboratory for Muscular Dystrophy Research. He is a recipient of many awards and grants for his valuable contributions and discoveries in major area of subject research. His international experience includes various programs, contributions and participation in different countries for diverse fields of study.  His research interests reflect in his wide range of publications in various national and international journals.  
Title
Cited by
Year
An atomic structure of human γ-secretase
X Bai, C Yan, G Yang, P Lu, D Ma, L Sun, R Zhou, SHW Scheres, Y ShiNature 525 (7568), 212-217, 2015201
551
2015
Three-dimensional structure of human γ-secretase
P Lu, X Bai, D Ma, T Xie, C Yan, L Sun, G Yang, Y Zhao, R Zhou, ...Nature 512 (7513), 166-170, 2014201
384
2014
Structure and mechanism of a glutamate–GABA antiporter
D Ma, P Lu, C Yan, C Fan, P Yin, J Wang, Y ShiNature 483 (7391), 632-636, 2012201
213
2012
Crystal structure and biochemical analyses reveal Beclin 1 as a novel membrane binding protein
W Huang, W Choi, W Hu, N Mi, Q Guo, M Ma, M Liu, Y Tian, P Lu, ...Cell research 22 (3), 473-489, 2012201
200
2012
L-glutamine provides acid resistance for Escherichia coli through enzymatic release of ammonia
P Lu, D Ma, Y Chen, Y Guo, GQ Chen, H Deng, Y ShiCell research 23 (5), 635-644, 2013201
197
2013
Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Y Wang, Y Huang, J Wang, C Cheng, W Huang, P Lu, YN Xu, P Wang, ...Nature 462 (7272), 467-472, 2009200
192
2009
Programmable design of orthogonal protein heterodimers
Z Chen, SE Boyken, M Jia, F Busch, D Flores-Solis, MJ Bick, P Lu, ...Nature 565 (7737), 106-111, 2019201
164
2019
Accurate computational design of multipass transmembrane proteins
P Lu, D Min, F DiMaio, KY Wei, MD Vahey, SE Boyken, Z Chen, JA Fallas, ...Science 359 (6379), 1042-1046, 2018201
153
2018
Computational design of transmembrane pores
C Xu, P Lu, TM Gamal El-Din, XY Pei, MC Johnson, A Uyeda, MJ Bick, ...Nature 585 (7823), 129-134, 2020202
111
2020
Crystal structure of a membrane-bound O-acyltransferase
D Ma, Z Wang, CN Merrikh, KS Lang, P Lu, X Li, H Merrikh, Z Rao, W XuNature 562 (7726), 286-290, 2018201
88
2018
Crystal structure of the γ-secretase component nicastrin
T Xie, C Yan, R Zhou, Y Zhao, L Sun, G Yang, P Lu, D Ma, Y ShiProceedings of the National Academy of Sciences 111 (37), 13349-13354, 2014201
74
2014
Structural basis for gating pore current in periodic paralysis
D Jiang, TM Gamal El-Din, C Ing, P Lu, R Pomes, N Zheng, WA CatterallNature 557 (7706), 590-594, 2018201
64
2018
Structure and mechanism of a eukaryotic transmembrane ascorbate-dependent oxidoreductase
P Lu, D Ma, C Yan, X Gong, M Du, Y ShiProceedings of the National Academy of Sciences 111 (5), 1813-1818, 2014201
64
2014
Substrate selectivity of the acid-activated glutamate/γ-aminobutyric acid (GABA) antiporter GadC from Escherichia coli
D Ma, P Lu, Y ShiJournal of Biological Chemistry 288 (21), 15148-15153, 2013201
50
2013
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
P Hosseinzadeh, PR Watson, TW Craven, X Li, S Rettie, F Pardo-Avila, ...Nature Communications 12 (1), 3384, 2021202
29
2021
Structure of the mRNA splicing complex component Cwc2: insights into RNA recognition
P Lu, G Lu, C Yan, L Wang, W Li, P YinBiochemical Journal 441 (2), 591-597, 2012201
19
2012
Cryo-EM structure of human Wntless in complex with Wnt3a
Q Zhong, Y Zhao, F Ye, Z Xiao, G Huang, M Xu, Y Zhang, X Zhan, K Sun, ...Nature Communications 12 (1), 4541, 2021202
15
2021
Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes
JA Peruzzi, J Steinkuehler, TQ Vu, TF Gunnels, P Lu, D Baker, NP KamatbioRxiv, 2022.06. 01.49474, 2022202
3
2022
Computational design of transmembrane proteins
J Zhu, P LuCurrent Opinion in Structural Biology 74, 10381, 0
2
2022
heterodimers
Z Chen, SE Boyken, M Jia, F Busch, D Flores-solis, MJ Bick, P Lu, ...Springer US, 20920
1
2019