Author

Peng Wu

Massachusetts Institute of Technology, Harvard University - Cited by 3,241 - Chemical Biology - Medicinal Chemistry - Organic Chemistry

Biography

Peng Wu is affiliated to Department of Chemical and Materials Engineering. He is a recipient of many awards and grants for his valuable contributions and discoveries in major area of subject research. His international experience includes various programs, contributions and participation in different countries for diverse fields of study.  His research interests reflect in his wide range of publications in various national and international journals.  
Title
Cited by
Year
FDA-approved small-molecule kinase inhibitors
P Wu, TE Nielsen, MH ClausenTrends in pharmacological sciences 36 (7), 422-439, 2015201
994
2015
Small-molecule kinase inhibitors: an analysis of FDA-approved drugs
P Wu, TE Nielsen, MH ClausenDrug discovery today 21 (1), 5-10, 2016201
480
2016
Reactivity and synthetic applications of multicomponent Petasis reactions
P Wu, M Givskov, TE NielsenChemical Reviews 119 (20), 11245-11290, 2019201
184
2019
Allosteric small-molecule kinase inhibitors
P Wu, MH Clausen, TE NielsenPharmacology & therapeutics 156, 59-68, 2015201
181
2015
Scaffold Diversity from N-Acyliminium Ions
P Wu, TE NielsenChemical reviews 117 (12), 7811-7856, 2017201
163
2017
A high-throughput platform to identify small-molecule inhibitors of CRISPR-Cas9
B Maji, SA Gangopadhyay, M Lee, M Shi, P Wu, R Heler, B Mok, D Lim, ...Cell 177 (4), 1067-1079. e19, 2019201
140
2019
Phosphorylation-inducing chimeric small molecules
SU Siriwardena, DNP Munkanatta Godage, VM Shoba, S Lai, M Shi, ...Journal of the American Chemical Society 142 (33), 14052-14057, 2020202
73
2020
Inhibition of RNA-binding proteins with small molecules
P WuNature Reviews Chemistry 4 (9), 441-458, 2020202
66
2020
Clinical and marketed proteasome inhibitors for cancer treatment
J Zhang, P Wu, Y HuCurrent medicinal chemistry 20 (20), 2537-2551, 2013201
57
2013
Design, synthesis and biological evaluation of novel 4-alkynyl-quinoline derivatives as PI3K/mTOR dual inhibitors
X Lv, H Ying, X Ma, N Qiu, P Wu, B Yang, Y HuEuropean Journal of Medicinal Chemistry 99, 36-50, 2015201
38
2015
A microwave-assisted multicomponent synthesis of substituted 3, 4-dihydroquinazolinones
MY Stevens, K Wieckowski, P Wu, RT Sawant, LR OdellOrganic & biomolecular chemistry 13 (7), 2044-2054, 2015201
21
2015
Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein–RNA Interaction of LIN28 and Let-7
L Borgelt, F Li, P Hommen, P Lampe, J Hwang, GL Goebel, S Sievers, ...ACS medicinal chemistry letters 12 (6), 893-898, 212
20
2021
Synthesis of hexahydropyrrolo [2, 1-a] isoquinoline compound libraries through a Pictet–Spengler cyclization/metal-catalyzed cross coupling/amidation sequence
R Petersen, AE Cohrt, MÅ Petersen, P Wu, MH Clausen, TE NielsenBioorganic & Medicinal Chemistry 23 (11), 2646-2649, 2015201
19
2015
Synthesis of 1, 4, 5 trisubstituted γ-lactams via a 3-component cascade reaction
MÅ Petersen, MA Mortensen, AE Cohrt, R Petersen, P Wu, ...Bioorganic & Medicinal Chemistry 23 (11), 2695-2698, 2015201
19
2015
Synthesis and biological evaluation of novel benzyl-substituted (S)-phenylalanine derivatives as potent dipeptidyl peptidase 4 inhibitors
Y Liu, M Si, L Tang, S Shangguan, H Wu, J Li, P Wu, X Ma, T Liu, Y HuBioorganic & medicinal chemistry 21 (18), 5679-5687, 2013201
17
2013
Petasis three-component reactions for the synthesis of diverse heterocyclic scaffolds
P Wu, TE NielsenDrug Discovery Today: Technologies 29, 27-33, 2018201
16
2018
Optochemical control of protein degradation
P Wu, D MannaChemBioChem 21 (16), 2250-2252, 2020202
15
2020
Identification of novel piperazinylquinoxaline derivatives as potent phosphoinositide 3-kinase (PI3K) inhibitors
P Wu, Y Su, X Guan, X Liu, J Zhang, X Dong, W Huang, Y HuPublic Library of Science 7 (8), e43171, 2012201
14
2012
Multicomponent petasis reaction for the synthesis of functionalized 2-aminothiophenes and thienodiazepines
J Hwang, L Borgelt, P WuACS Combinatorial Science 22 (10), 495-499, 2020202
13
2020
A metal-catalyzed enyne-cyclization step for the synthesis of bi-and tricyclic scaffolds amenable to molecular library production
P Wu, MÅ Petersen, AE Cohrt, R Petersen, R Morgentin, H Lemoine, ...Organic & Biomolecular Chemistry 14 (29), 6947-6950, 2016201
13
2016

Referred From: https://scholar.google.com/citations?user=VgVj7EwAAAAJ&hl=en

Cited by
Citations 3241
h-index 20
i10-index 38
Open Access Journals