Author

Antonella Casola

Professor of Pediatrics, University of Texas Medical Branch, Galveston - Cited by 9,242 - Infectious Diseases

Biography

Dr. Casola is a physician-scientist specialized in pediatric infectious diseases, with research expertise in the area of respiratory etc. Her research is focused on the investigation of viral- and host-specific mechanisms that contribute to the pathogenesis of respiratory viral infections. Over the past several years, she has identified several inducible intracellular signaling pathways activated by respiratory syncytial virus (RSV) in airway epithelial cells with particular emphasis on the role of reactive oxygen species in RSV induced lung inflammation both in vitro and in vivo. 
Title
Cited by
Year
Antiviral and immunomodulatory activity of silver nanoparticles in experimental RSV infection
D Morris, M Ansar, J Speshock, T Ivanciuc, Y Qu, A Casola, RP GarofaloViruses 11 (8), 732, 2019201
162
2019
Role of hydrogen sulfide in NRF2-and sirtuin-dependent maintenance of cellular redox balance
T Corsello, N Komaravelli, A CasolaAntioxidants 7 (10), 129, 2018201
113
2018
Respiratory syncytial virus infection changes cargo composition of exosome released from airway epithelial cells
HS Chahar, T Corsello, AS Kudlicki, N Komaravelli, A CasolaScientific reports 8 (1), 387, 2018201
90
2018
Hydrogen sulfide: a novel player in airway development, pathophysiology of respiratory diseases, and antiviral defenses
N Bazhanov, M Ansar, T Ivanciuc, RP Garofalo, A CasolaAmerican journal of respiratory cell and molecular biology 57 (4), 403-410, 2017201
85
2017
Respiratory syncytial virus infection down-regulates antioxidant enzyme expression by triggering deacetylation-proteasomal degradation of Nrf2
N Komaravelli, B Tian, T Ivanciuc, N Mautemps, AR Brasier, RP Garofalo, ...Free Radical Biology and Medicine 88, 391-403, 2015201
78
2015
Hydrogen sulfide is an antiviral and antiinflammatory endogenous gasotransmitter in the airways. Role in respiratory syncytial virus infection
T Ivanciuc, E Sbrana, M Ansar, N Bazhanov, C Szabo, A Casola, ...American journal of respiratory cell and molecular biology 55 (5), 684-696, 2016201
77
2016
Respiratory syncytial virus infection triggers epithelial HMGB1 release as a damage-associated molecular pattern promoting a monocytic inflammatory response
YM Hosakote, AR Brasier, A Casola, RP Garofalo, A KuroskyJournal of virology 90 (21), 9618-9631, 2016201
74
2016
Broad-range antiviral activity of hydrogen sulfide against highly pathogenic RNA viruses
N Bazhanov, O Escaffre, AN Freiberg, RP Garofalo, A CasolaScientific reports 7 (1), 41029, 2017201
59
2017
Respiratory syncytial virus induces NRF2 degradation through a promyelocytic leukemia protein‐ring finger protein 4 dependent pathway
N Komaravelli, M Ansar, RP Garofalo, A CasolaFree Radical Biology and Medicine 113, 494-504, 2017201
48
2017
Thiol-activated hydrogen sulfide donors antiviral and anti-inflammatory activity in respiratory syncytial virus infection
N Bazhanov, T Ivanciuc, H Wu, M Garofalo, J Kang, M Xian, A CasolaViruses 10 (5), 249, 2018201
31
2018
Increased lung catalase activity confers protection against experimental RSV infection
M Ansar, T Ivanciuc, RP Garofalo, A CasolaScientific reports 10 (1), 3653, 2020202
23
2020
Methods for treating viral infections using hydrogen sulfide donors
A Casola, O Escaffre, AN Freiberg, RP GarofaloUS Patent 9,504,701, 2016201
21
2016
Methods for treating viral infections using hydrogen sulfide donors
A Casola, RP GarofaloUS Patent 9,616,076, 2017201
19
2017
Human metapneumovirus infection of airway epithelial cells is associated with changes in core metabolic pathways
Y Zhao, HS Chahar, N Komaravelli, A Dossumbekova, A CasolaVirology 531, 183-191, 2019201
16
2019
Selective blockade of TNFR1 improves clinical disease and bronchoconstriction in experimental RSV infection
DR Morris, M Ansar, T Ivanciuc, Y Qu, A Casola, RP GarofaloViruses (10), 1176, 2020202
12
2020
12
2019
Oxidative stress in Nipah virus-infected human small airway epithelial cells
O Escaffre, H Halliday, V Borisevich, A Casola, B RockxThe Journal of General Virology 96 (Pt 10), 2961, 2015201
11
2015