Author

Mario H Hirata

Universidade de Sao Paulo - Cited by 7,896 - Genomics - epigenomica - farmacogenomica e epifarmacogenomica

Biography

Undergrasutate course : pharmacy and biochemistry Master in pharmacy PhD in Sciences area of experimental nutrition Assistent Professor in the Department of clinical and toxicological Analysis in the Univesity of Sao Paulo:1981-1990 Associated professor in the department of clinical and toxicological anaylis in the University of Sáo Paulo, 1991- 2005 Professor in clinical biochemistry at Department of clinical and toxicological analysis in the University of Sao Paulo , 2005- present More than 100 paper published in the filed of clinical analysis and physiopathology in infectious diseases.
Title
Cited by
Year
MHC Variants Associated With Symptomatic Versus Asymptomatic SARS-CoV-2 Infection in Highly Exposed Individuals
EC Castelli, MV De Castro, MS Naslavsky, MO Scliar, NSB Silva, ...Frontiers in Immunology 12, 742881, 2021202
37
2021
MiR-3168, miR-6125, and miR-4718 as potential predictors of cisplatin-induced nephrotoxicity in patients with head and neck cancer
JCF Quintanilha, MA Cursino, JB Borges, NG Torso, LB Bastos, ...BMC cancer 21 (1), 575, 2021202
15
2021
Genomics, epigenomics and pharmacogenomics of familial hypercholesterolemia (FHBGEP): A study protocol
JB Borges, VF de Oliveira, GM Ferreira, B Los, TKAA Barbosa, ...Research in social and administrative pharmacy 17 (7), 1347-1355, 2021202
14
2021
P2x7 receptor signaling blockade reduces lung inflammation and necrosis during severe experimental tuberculosis
I Santiago-Carvalho, G Almeida-Santos, CCB Bomfim, PC Souza, ...Frontiers in Cellular and Infection Microbiology 11, 672472, 2021202
13
2021
SARS-COV-2 Mpro conformational changes induced by covalently bound ligands
GM Ferreira, T Kronenberger, AK Tonduru, RDC Hirata, MH Hirata, ...Journal of Biomolecular Structure and Dynamics 40 (22), 12347-12357, 2022202
13
2022
9
2021
Association of variants in MYH7, MYBPC3 and TNNT2 with sudden cardiac death-related risk factors in Brazilian patients with hypertrophic cardiomyopathy
AA Mori, LR de Castro, RH Bortolin, GM Bastos, VF de Oliveira, ...Forensic Science International: Genetics 52, 10247, 2021202
8
2021
Pharmacogenomics of statins: lipid response and other outcomes in Brazilian cohorts
C Dagli-Hernandez, Y Zhou, VM Lauschke, FDV Genvigir, TDC Hirata, ...Pharmacological Reports 4 (1), 4-66, 2022202
7
2022
Effect of statins on lipid metabolism-related microRNA expression in HepG2 cells
A Cerda, RH Bortolin, V Manriquez, L Salazar, T Zambrano, CM Fajardo, ...Pharmacological Reports 73, 88-880, 2021202
6
2021
MUC22, HLA-A, and HLA-DOB variants and COVID-19 in resilient super-agers from Brazil
EC Castelli, MV de Castro, MS Naslavsky, MO Scliar, NSB Silva, ...Frontiers in Immunology 13, 975918, 2022202
4
2022
Inhibitor induced conformational changes in SARS-CoV-2 papain-like protease
GM Ferreira, T Pillaiyar, MH Hirata, A Poso, T KronenbergerScientific Reports 12 (1), 11585, 2022202
4
2022
Isohemigossypolone: Antiophidic properties of a naphthoquinone isolated from Pachira aquatica Aubl.
SAPB Vieira, BM Dos Santos, CDS Júnior, VF de Paula, MSR Gomes, ...Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2021202
4
2021
Toll‐like receptor inflammatory cascade and the development of diabetic kidney disease in children and adolescents with type 1 diabetes
TR de Melo, KSC de Souza, MAG Ururahy, RH Bortolin, JF Bezerra, ...Journal of Paediatrics and Child Health 58 (6), 996-1000, 2022202
3
2022
Dynamics of the personalities of PCSK9 on missense variants (rs505151 and rs562556) from elderly cohort studies in Brazil
V Galvão Lopes, V Fernandes de Oliveira, L Mendonça Munhoz Dati, ...Journal of Biomolecular Structure and Dynamics, 1-9, 20220
3
2023
Functional analysis of PCSK9 3′UTR variants and mRNA–miRNA interactions in patients with familial hypercholesterolemia
Functional analysis of PCSK9 ′UTR variants and mRNA–miRNA interactions in patients with familial hypercholesterolemiaB Los, JB Borges, VF Oliveira, RCC Freitas, C Dagli-Hernandez, ...Epigenomics 1 (10), 779-791, 2021202
3
2021
LDLR missense variants disturb structural conformation and LDLR activity in T-lymphocytes of familial hypercholesterolemia patients
TKA Barbosa, RDC Hirata, GM Ferreira, JB Borges, VF de Oliveira, ...Gene 85, 147084, 20220
3
2023
Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia
C Dagli-Hernandez, JB Borges, ESR Marçal, RCC de Freitas, AA Mori, ...Pharmaceutics 14 (5), 944, 0
2
2022
Cardiovascular pharmacogenomics: an update on clinical studies of antithrombotic drugs in Brazilian patients
TDC Hirata, C Dagli-Hernandez, FDV Genvigir, VM Lauschke, Y Zhou, ...Molecular Diagnosis & Therapy 5 (6), 735-755, 010
2
2021
Epigenetic regulation of transcription factor binding motifs promotes Th1 response in Chagas disease cardiomyopathy
P Brochet, BM Ianni, L Laugier, AF Frade, JP Silva Nunes, PC Teixeira, ...Frontiers in Immunology 13, 4536, 0
2
2022
Carnitine palmitoyl transferase I: Conformational changes induced by long-chain fatty acyl CoA ligands
VG Lopes, A de Britto Chaves Filho, MY Yoshinaga, MH Hirata, ...Journal of Molecular Graphics and Modelling 2, 0825, 2022202
1
2022