Author

Titus J Boggon

Yale University School of Medicine - Cited by 37,537

Biography

Titus J Boggon as complected his Ph.D from Yale University School of Medicine working as  Associate Professor of Pharmacology and of Molecular Biophysics and Biochemistry at The Yale Cancer Center.The Boggon lab is interested in using structural biology approaches to help understand functional alterations that impact human disease
Title
Cited by
Year
Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial–mesenchymal transition
S Zhao, S Bellone, S Lopez, D Thakral, C Schwab, DP English, J Black, ...Proceedings of the National Academy of Sciences 113 (43), 12238-12243, 2016201
175
2016
Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p. Q575E)
J Park, J Yang, AT Wenzel, A Ramachandran, WJ Lee, JC Daniels, J Kim, ...Blood, The Journal of the American Society of Hematology 130 (12), 1430-1440, 2017201
126
2017
Data publication with the structural biology data grid supports live analysis
PA Meyer, S Socias, J Key, E Ransey, EC Tjon, A Buschiazzo, M Lei, ...Nature communications 7 (1), 10882, 2016201
101
2016
MAST1 drives cisplatin resistance in human cancers by rewiring cRaf-independent MEK activation
L Jin, J Chun, C Pan, D Li, R Lin, GN Alesi, X Wang, HB Kang, L Song, ...Cancer cell 34 (2), 315-330. e7, 2018201
80
2018
Tetrameric acetyl-CoA acetyltransferase 1 is important for tumor growth
J Fan, R Lin, S Xia, D Chen, SE Elf, S Liu, Y Pan, H Xu, Z Qian, M Wang, ...Molecular cell 64 (5), 859-8, 2016201
74
2016
Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy
L Zammataro, S Lopez, S Bellone, F Pettinella, E Bonazzoli, E Perrone, ...Proceedings of the National Academy of Sciences 116 (45), 22730-22736, 2019201
58
2019
Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension
S Vilarinho, S Sari, G Yilmaz, AL Stiegler, TJ Boggon, D Jain, G Akyol, ...Hepatology 63 (6), 1977-1986, 2016201
55
2016
Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin
S Elf, R Lin, S Xia, Y Pan, C Shan, S Wu, S Lonial, M Gaddh, ML Arellano, ...Oncogene 36 (2), 254-262, 2017201
51
2017
Structural basis for noncanonical substrate recognition of cofilin/ADF proteins by LIM kinases
S Hamill, HJ Lou, BE Turk, TJ BoggonMolecular cell 62 (3), 397-408, 2016201
48
2016
The crystal structure of pseudokinase PEAK1 (Sugen kinase 269) reveals an unusual catalytic cleft and a novel mode of kinase fold dimerization
BH Ha, TJ BoggonJournal of Biological Chemistry 293 (5), 1642-1650, 2018201
46
2018
Integrated genomic analyses of cutaneous T-cell lymphomas reveal the molecular bases for disease heterogeneity
J Park, J Daniels, T Wartewig, KG Ringbloom, ME Martinez-Escala, ...Blood, The Journal of the American Society of Hematology 138 (14), 1225-1236, 2021202
43
2021
γ-6-Phosphogluconolactone, a byproduct of the oxidative pentose phosphate pathway, contributes to AMPK activation through inhibition of PP2A
X Gao, L Zhao, S Liu, Y Li, S Xia, D Chen, M Wang, S Wu, Q Dai, H Vu, ...Molecular cell 76 (6), 857-871. e9, 2019201
36
2019
Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output
CJ Miller, HJ Lou, C Simpson, B van de Kooij, BH Ha, OS Fisher, ...PLoS biology 17 (3), e2006540, 2019201
35
2019
Mutations in ILK, encoding integrin-linked kinase, are associated with arrhythmogenic cardiomyopathy
A Brodehl, S Rezazadeh, T Williams, NM Munsie, D Liedtke, T Oh, ...Translational Research 208, 15-, 2019201
29
2019
PAK6 targets to cell–cell adhesions through its N-terminus in a Cdc42-dependent manner to drive epithelial colony escape
EM Morse, X Sun, JR Olberding, BH Ha, TJ Boggon, DA CalderwoodJournal of cell science 129 (2), 380-393, 2016201
28
2016
CDC42 binds PAK4 via an extended GTPase-effector interface
BH Ha, TJ BoggonProceedings of the National Academy of Sciences 115 (3), 531-536, 2018201
28
2018
Mutant and wild-type isocitrate dehydrogenase 1 share enhancing mechanisms involving distinct tyrosine kinase cascades in cancer
D Chen, S Xia, M Wang, R Lin, Y Li, H Mao, M Aguiar, CA Famulare, ...Cancer discovery 9 (6), 756-777, 2019201
25
2019
Mutations in TFAP2B and previously unimplicated genes of the BMP, Wnt, and Hedgehog pathways in syndromic craniosynostosis
AT Timberlake, SC Jin, C Nelson-Williams, R Wu, CG Furey, B Islam, ...Proceedings of the National Academy of Sciences 116 (30), 15116-15121, 2019201
24
2019
p190RhoGAP proteins contain pseudoGTPase domains
AL Stiegler, TJ BoggonNature communications 8 (1), 506, 2017201
22
2017
Constrained chromatin accessibility in PU. 1-mutated agammaglobulinemia patients
C Le Coz, DN Nguyen, C Su, BE Nolan, AV Albrecht, S Xhani, D Sun, ...Journal of Experimental Medicine 8 (7), e20201750, 202
21
2021

Referred From: https://scholar.google.com/citations?user=SKiaRN0AAAAJ&hl=en

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Citations 37537
h-index 63
i10-index 125
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