Author

Alfredo Franco-Obregón

Associate Professor, National University Singapore, Department of Surgery, iHealthTech - Cited by 4,285 - Biophysics - Mechanobiology - Electrophysiology - Sports Physiology - Tissue Engineering

Biography

The BICEPS lab focusses on designing and developing technologies and clinical approaches to promote the maintenance of the body’s key mechanosensitive tissues in states of inherent mechanical dysfunction such as occurs in old age, or in response to imposed immobilization, because of injury, disease or human spaceflight. We are also exploiting magnetic fields to promote mitochondrial respiration and downstream developmental and survival adaptations via a process known as Magnetic Mitohormesis.
Title
Cited by
Year
Low intensity and frequency pulsed electromagnetic fields selectively impair breast cancer cell viability
S Crocetti, C Beyer, G Schade, M Egli, J Fröhlich, A Franco-ObregónPloS one 8 (9), e72944, 2013201
141
2013
Regenerative therapies for equine degenerative joint disease: a preliminary study
S Broeckx, M Zimmerman, S Crocetti, M Suls, T Marien, SJ Ferguson, ...PloS one 9 (1), e85917, 2014201
124
2014
Noncytotoxic artificial bacterial flagella fabricated from biocompatible ORMOCOMP and iron coating
F Qiu, L Zhang, KE Peyer, M Casarosa, A Franco-Obregón, H Choi, ...Journal of Materials Chemistry B 2 (4), 357-362, 2014201
74
2014
A new mechanobiological era: microfluidic pathways to apply and sense forces at the cellular level
F Kurth, K Eyer, A Franco-Obregón, PS DittrichCurrent opinion in chemical biology 16 (3-4), 400-408, 2012201
73
2012
Enhancement of mesenchymal stem cell chondrogenesis with short-term low intensity pulsed electromagnetic fields
D Parate, A Franco-Obregón, J Fröhlich, C Beyer, AA Abbas, T Kamarul, ...Scientific reports 7 (1), 9421, 2017201
70
2017
The microbiome-mitochondrion connection: common ancestries, common mechanisms, common goals
A Franco-Obregón, JA GilbertMsystems 2 (3), e00018-17, 2017201
67
2017
Pulsed electromagnetic fields potentiate the paracrine function of mesenchymal stem cells for cartilage regeneration
D Parate, ND Kadir, C Celik, EH Lee, JHP Hui, A Franco-Obregón, Z YangStem cell research & therapy 11, 1-16, 2020202
55
2020
Graphene-induced osteogenic differentiation is mediated by the integrin/FAK axis
H Xie, T Cao, A Franco-Obregón, V RosaInternational Journal of Molecular Sciences 20 (3), 574, 2019201
49
2019
Calcium‐dependent deceleration of the cell cycle in muscle cells by simulated microgravity
TB Damm, S Richard, S Tanner, F Wyss, M Egli, A Franco‐ObregónThe FASEB Journal 27 (5), 2045-2054, 2013201
38
2013
Gravitational force modulates G2/M phase exit in mechanically unloaded myoblasts
T Benavides Damm, A Franco-Obregón, M EgliCell Cycle 12 (18), 3001-3012, 2013201
35
2013
TRP channels in brown and white adipogenesis from human progenitors: new therapeutic targets and the caveats associated with the common antibiotic, streptomycin
A Goralczyk, M van Vijven, M Koch, C Badowski, MS Yassin, SA Toh, ...The FASEB Journal 31 (8), 3251-3266, 2017201
33
2017
Ambient and supplemental magnetic fields promote myogenesis via a TRPC1-mitochondrial axis: evidence of a magnetic mitohormetic mechanism
JLY Yap, YK Tai, J Fröhlich, CHH Fong, JN Yin, ZL Foo, S Ramanan, ...The FASEB Journal (11), 12853, 2019201
33
2019
Bio-inspired microrobots
F Qiu, L Zhang, S Tottori, K Marquardt, K Krawczyk, A Franco-Obregón, ...Materials Today 15 (10), 463, 2012201
28
2012
Transient receptor potential vanilloid 2‐mediated shear‐stress responses in C2C12 myoblasts are regulated by serum and extracellular matrix
F Kurth, A Franco‐Obregón, M Casarosa, SK Küster, K Wuertz‐Kozak, ...The FASEB Journal 29 (11), 4726-4737, 2015201
24
2015
Equine epidermis: a source of epithelial-like stem/progenitor cells with in vitro and in vivo regenerative capacities
SY Broeckx, S Maes, T Martinello, D Aerts, K Chiers, T Mariën, M Patruno, ...Stem Cells and Development 23 (10), 1134-1148, 2014201
22
2014
Impedance flow cytometry gauges proliferative capacity by detecting TRPC1 expression
S Crocetti, C Beyer, S Unternährer, T Benavides Damm, ...Cytometry Part A 85 (6), 525-536, 2014201
21
2014
Chondrogenic priming at reduced cell density enhances cartilage adhesion of equine allogeneic MSCs-a loading sensitive phenomenon in an organ culture study with 180 explants
JH Spaas, SY Broeckx, K Chiers, SJ Ferguson, M Casarosa, ...Cellular Physiology and Biochemistry 37 (2), 651-665, 151
20
2015
Magnetic fields modulate metabolism and gut microbiome in correlation withPgc-1 alpha expression: Follow-up to an in vitro magnetic mitohormetic study
YK Tai, C Ng, K Purnamawati, J Lye Yee Yap, JN Yin, C Wong, BK Patel, ...The FASEB Journal 34 (8), 11143-11167, 2020202
18
2020
Directionalities of magnetic fields and topographic scaffolds synergise to enhance MSC chondrogenesis
C Celik, A Franco-Obregón, EH Lee, JHP Hui, Z YangActa Biomaterialia 119, 169-183, 2021202
17
2021
TRPC6 in simulated microgravity of intervertebral disc cells
A Franco-Obregón, E Cambria, H Greutert, T Wernas, W Hitzl, M Egli, ...European Spine Journal 27, 2621-2630, 2018201
15
2018

Referred From: https://scholar.google.com/citations?user=koc44rwAAAAJ&hl=en

Cited by
Citations 4285
h-index 33
i10-index 56
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