Author

Bradley B Keller

Professor of Pediatrics, Bioengineering, and Pharmacology & Toxicology - Cited by 6,794 - Cardiovascular Development - Pediatric Cardiology - Bioengineering

Biography

Dr. Keller is a clinician-investigator who provides care to children and adults with congenital heart disease throughout Kentucky. He is also an expert in the causes of congenital heart disease and in the development and testing of novel technologies for children and adults with heart disease.
Title
Cited by
Year
Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence
Y Tan, Z Zhang, C Zheng, KA Wintergerst, BB Keller, L CaiNature Reviews Cardiology 17 (9), 585-607, 2020202
333
2020
Metallothionein is downstream of Nrf2 and partially mediates sulforaphane prevention of diabetic cardiomyopathy
J Gu, Y Cheng, H Wu, L Kong, S Wang, Z Xu, Z Zhang, Y Tan, BB Keller, ...Diabetes 66 (2), 529-542, 2017201
127
2017
Nrf2: redox and metabolic regulator of stem cell state and function
X Dai, X Yan, KA Wintergerst, L Cai, BB Keller, Y TanTrends in Molecular Medicine 26 (2), 185-200, 2020202
115
2020
The myocardial regenerative potential of three-dimensional engineered cardiac tissues composed of multiple human iPS cell-derived cardiovascular cell lineages
H Masumoto, T Nakane, JP Tinney, F Yuan, F Ye, WJ Kowalski, ...Scientific reports 6 (1), 1-10, 2016201
101
2016
Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways
X Wang, X Chen, W Zhou, H Men, T Bao, Y Sun, Q Wang, Y Tan, ...Acta Pharmaceutica Sinica B 12 (2), 708-722, 2022202
75
2022
Impact of cell composition and geometry on human induced pluripotent stem cells-derived engineered cardiac tissue
T Nakane, H Masumoto, JP Tinney, F Yuan, WJ Kowalski, F Ye, ...Scientific reports 7 (1), 45641, 2017201
68
2017
Inhibition of p53 prevents diabetic cardiomyopathy by preventing early-stage apoptosis and cell senescence, reduced glycolysis, and impaired angiogenesis
J Gu, S Wang, H Guo, Y Tan, Y Liang, A Feng, Q Liu, C Damodaran, ...Cell death & disease 9 (2), 82, 2018201
68
2018
Zinc as a countermeasure for cadmium toxicity
H Yu, J Zhen, J Leng, L Cai, H Ji, BB KellerActa Pharmacologica Sinica 42 (3), 340-346, 2021202
33
2021
Right ventricular dysfunction and remodeling in diabetic cardiomyopathy
Y Kang, S Wang, J Huang, L Cai, BB KellerAmerican Journal of Physiology-Heart and Circulatory Physiology 316 (1 …, 2019201
25
2019
Sulforaphane prevents right ventricular injury and reduces pulmonary vascular remodeling in pulmonary arterial hypertension
Y Kang, G Zhang, EC Huang, J Huang, J Cai, L Cai, S Wang, BB KellerAmerican Journal of Physiology-Heart and Circulatory Physiology 318 (4 …, 2020202
25
2020
Three-dimensional reconstruction of intracardiac anatomy using CTA and surgical planning for double outlet right ventricle: early experience at a tertiary care congenital heart …
PB Dydynski, C Kiper, D Kozik, BB Keller, E Austin, B HollandWorld Journal for Pediatric and Congenital Heart Surgery 7 (4), 467-474, 2016201
22
2016
Challenging cardiac function post-spinal cord injury with dobutamine
KM DeVeau, EK Martin, NT King, A Shum-Siu, BB Keller, CR West, ...Autonomic Neuroscience 9, 19-24, 181
20
2018
Adipose-derived cells improve left ventricular diastolic function and increase microvascular perfusion in advanced age
NQ Kelm, JE Beare, F Yuan, M George, CM Shofner, BB Keller, JB Hoying, ...PLoS One 13 (8), e02934, 181
20
2018
Exacerbation of diabetic cardiac hypertrophy in OVE26 mice by angiotensin II is associated with JNK/c-Jun/miR-221-mediated autophagy inhibition
LB Qian, SZ Jiang, XQ Tang, J Zhang, YQ Liang, HT Yu, J Chen, Z Xu, ...Oncotarget 8 (63), 106661, 2017201
19
2017
Chronic optical pacing conditioning of h-iPSC engineered cardiac tissues
M Dwenger, WJ Kowalski, F Ye, F Yuan, JP Tinney, S Setozaki, T Nakane, ...Journal of tissue engineering 10, 204314198448, 2019201
17
2019
Utilizing contrast-enhanced ultrasound imaging for evaluating fatty liver disease progression in pre-clinical mouse models
H Pandit, JP Tinney, Y Li, G Cui, S Li, BB Keller, RCG Martin IIUltrasound in Medicine & Biology 45 (2), 549-557, 2019201
16
2019
Quantification of cardiomyocyte alignment from three-dimensional (3D) confocal microscopy of engineered tissue
WJ Kowalski, F Yuan, T Nakane, H Masumoto, M Dwenger, F Ye, ...Microscopy and Microanalysis 23 (4), 826-842, 2017201
13
2017
Asymmetry in mechanosensitive gene expression during aortic arch morphogenesis
C Karakaya, S Goktas, M Celik, WJ Kowalski, BB Keller, K PekkanScientific reports 8 (1), 16948, 2018201
12
2018
Zinc protects against cadmium-induced toxicity in neonatal murine engineered cardiac tissues via metallothionein-dependent and independent mechanisms
H Yu, J Zhen, J Xu, L Cai, J Leng, H Ji, BB KellerActa pharmacologica sinica 41 (5), 638-649, 2020202
11
2020
Engineered cardiac tissues: a novel in vitro model to investigate the pathophysiology of mouse diabetic cardiomyopathy
X Wang, X Chen, H Yu, Y Tan, Q Lin, BB Keller, Y Zheng, L CaiActa Pharmacologica Sinica 42 (6), 932-941, 2021202
10
2021

Referred From: https://scholar.google.com/citations?user=CguFwgIAAAAJ&hl=en

Cited by
Citations 6794
h-index 45
i10-index 114
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