University of Pavia; - Cited by 6,210 - Calcium Signalling - Endothelial Progenitor Cells - Hydrogen Sulphide - Store-Operated Calcium Entry - Ca2+ Oscillations
Biography
I am investigating the role of TRP channels and store-operated Ca2+ entry (Stim1 and Orai1) in endothelial progenitor cells (EPCs) from both peripheral and umbilical cord blood. We are also studying the remodeling of the Ca2+ toolkit in EPCs from human cancer (kidney and breast) patients. Ca2+ channels might be a feasible target for both regenerative medicine and anti-cancer strategies. We use Ca2+ imaging and patch-clamp, Western Blotting and immunofluorescence, qRT-PCR and gene silencing.
Targeting endolysosomal two-pore channels to treat cardiovascular disorders in the novel COronaVIrus Disease 19F Moccia, S Negri, P Faris, A Perna, A De Luca, T Soda, R Berra-Romani, ...Frontiers in Physiology 12, 629119, 212
M Vismara, M Zarà, S Negri, J Canino, I Canobbio, SS Barbieri, F Moccia, ...Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1868 (1), 118886, 2021202