Author

Francesco Moccia

University of Pavia; - Cited by 6,210 - Calcium Signalling - Endothelial Progenitor Cells - Hydrogen Sulphide - Store-Operated Calcium Entry - Ca2+ Oscillations

Biography

I am investigating the role of TRP channels and store-operated Ca2+ entry (Stim1 and Orai1) in endothelial progenitor cells (EPCs) from both peripheral and umbilical cord blood. We are also studying the remodeling of the Ca2+ toolkit in EPCs from human cancer (kidney and breast) patients. Ca2+ channels might be a feasible target for both regenerative medicine and anti-cancer strategies. We use Ca2+ imaging and patch-clamp, Western Blotting and immunofluorescence, qRT-PCR and gene silencing.
Title
Cited by
Year
Reactive Oxygen Species and Endothelial Ca2+ Signaling: Brothers in Arms or Partners in Crime?
S Negri, P Faris, F MocciaInternational Journal of Molecular Sciences 22 (18), 9821, 2021202
29
2021
Understanding the heart-brain axis response in COVID-19 patients: A suggestive perspective for therapeutic development
V Lionetti, S Bollini, R Coppini, A Gerbino, A Ghigo, G Iaccarino, ...Pharmacological Research 168, 105581, 2021202
23
2021
Nicotinic acid adenine dinucleotide phosphate activates two‐pore channel TPC1 to mediate lysosomal Ca2+ release in endothelial colony‐forming cells
F Moccia, E Zuccolo, F Di Nezza, G Pellavio, PS Faris, S Negri, A De Luca, ...Journal of Cellular Physiology 236 (1), 688-705, 202
21
2021
Targeting endolysosomal two-pore channels to treat cardiovascular disorders in the novel COronaVIrus Disease 2019
Targeting endolysosomal two-pore channels to treat cardiovascular disorders in the novel COronaVIrus Disease 19F Moccia, S Negri, P Faris, A Perna, A De Luca, T Soda, R Berra-Romani, ...Frontiers in Physiology 12, 629119, 212
20
2021
Platelet-derived extracellular vesicles regulate cell cycle progression and cell migration in breast cancer cells
M Vismara, M Zarà, S Negri, J Canino, I Canobbio, SS Barbieri, F Moccia, ...Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1868 (1), 118886, 2021202
19
2021
17
2021
Hydrogen Sulfide-Evoked Intracellular Ca2+ Signals in Primary Cultures of Metastatic Colorectal Cancer Cells
P Faris, F Ferulli, M Vismara, M Tanzi, S Negri, A Rumolo, K Lefkimmiatis, ...Cancers 12 (11), 3338, 2020202
16
2020
Extracellular vesicles (EVs) in ischemic conditioning and angiogenesis: Focus on endothelial derived EVs
E Alfì, C Thairi, S Femmino, G Alloatti, F Moccia, MF Brizzi, P Pagliaro, ...Vascular Pharmacology 140, 106873, 2021202
15
2021
15
2022
Endolysosomal Ca2+ signaling in cardiovascular health and disease
S Negri, P Faris, F MocciaInternational Review of Cell and Molecular Biology 363, 203-269, 2021202
14
2021
The human amniotic fluid stem cell secretome triggers intracellular Ca2+ oscillations, NF‐κB nuclear translocation and tube formation in human endothelial colony …
V Balducci, P Faris, C Balbi, A Costa, S Negri, V Rosti, S Bollini, F MocciaJournal of Cellular and Molecular Medicine 25 (16), 8074-8086, 2021202
14
2021
The heterogeneity of cancer endothelium: The relevance of angiogenesis and endothelial progenitor cells in cancer microenvironment
G Armani, E Pozzi, A Pagani, C Porta, M Rizzo, D Cicognini, B Rovati, ...Microvascular Research 138, 104189, 2021202
12
2021
Store-Operated Ca2+ Entry Is Up-Regulated in Tumour-Infiltrating Lymphocytes from Metastatic Colorectal Cancer Patients
P Faris, A Rumolo, L Tapella, M Tanzi, A Metallo, F Conca, S Negri, ...Cancers 14 (14), 3312, 2022202
6
2022
Towards novel geneless approaches for therapeutic angiogenesis
F Moccia, MR Antognazza, F LodolaFrontiers in Physiology 11, 1189, 2021202
6
2021
GABAA and GABAB Receptors Mediate GABA-Induced Intracellular Ca2+ Signals in Human Brain Microvascular Endothelial Cells
S Negri, F Scolari, M Vismara, V Brunetti, P Faris, G Terribile, G Sancini, ...Cells 11 (23), 380, 2022202
6
2022
Ablation of collagen VI leads to the release of platelets with altered function
V Abbonante, C Gruppi, M Battiston, A Zulian, CA Di Buduo, M Chrisam, ...Blood Advances 5 (23), 5150-5163, 2021202
4
2021
Optical excitation of organic semiconductors as a highly selective strategy to induce vascular regeneration and tissue repair
F Moccia, S Negri, P Faris, C Ronchi, F LodolaVascular Pharmacology 1, 106998, 2022202
4
2022
Nicotinic Acid Adenine Dinucleotide Phosphate Induces Intracellular Ca2+ Signalling and Stimulates Proliferation in Human Cardiac Mesenchymal Stromal Cells
P Faris, C Casali, S Negri, L Iengo, M Biggiogera, AS Maione, F MocciaFrontiers in Cell and Developmental Biology 10, 8703, 2022202
4
2022
Knocking out TMEM38B in human foetal osteoblasts hFOB 1.19 by CRISPR/Cas9: A model for recessive OI type XIV
L Leoni, F Tonelli, R Besio, R Gioia, F Moccia, A Rossi, A ForlinoPlos one 16 (9), e025725, 2021202
4
2021