Author

Johnson Rajasingh

University of Tennessee Health Science Center - Cited by 3,357 - Biology - Stem cells - Regenerative Medicine

Biography

My research interest is focusing on novel strategies to enhance the therapeutic benefits of stem cells in regenerative medicine particularly repairing the heart, lung and dental injuries. Currently, we are reprogramming somatic cells (normal and patients) by using mRNA of pluripotent factors to generate induced pluripotent stem cells (iPSCs) and further differentiate into various kinds of cells, including cardiomyocytes, mesenchymal stem cells and osteocytes; Epigenetic studies on lung injury.
Title
Cited by
Year
Exosomes: new molecular targets of diseases
S Samanta, S Rajasingh, N Drosos, Z Zhou, B Dawn, J RajasinghActa Pharmacologica Sinica 39 (4), 501-513, 2018201
299
2018
Macrophage polarization in response to epigenetic modifiers during infection and inflammation
U Patel, S Rajasingh, S Samanta, T Cao, B Dawn, J RajasinghDrug discovery today 22 (1), 186-193, 2017201
152
2017
Extracellular vesicles in cardiovascular theranostics
Y Bei, S Das, RS Rodosthenous, P Holvoet, M Vanhaverbeke, ...Theranostics 7 (17), 4168, 2017201
123
2017
Adult stem cells for regenerative therapy
N Gurusamy, A Alsayari, S Rajasingh, J RajasinghProgress in molecular biology and translational science 160, 1-22, 2018201
102
2018
Left atrial appendage closure and systemic homeostasis: the LAA HOMEOSTASIS study
D Lakkireddy, M Turagam, MR Afzal, J Rajasingh, D Atkins, B Dawn, ...Journal of the American College of Cardiology 71 (2), 135-144, 2018201
83
2018
Nanodiamond-based injectable hydrogel for sustained growth factor release: preparation, characterization and in vitro analysis
S Pacelli, F Acosta, AR Chakravarti, SG Samanta, J Whitlow, S Modaresi, ...Acta biomaterialia 58, 479-491, 2017201
68
2017
Role of human mesenchymal stem cells in regenerative therapy
J Vasanthan, N Gurusamy, S Rajasingh, V Sigamani, S Kirankumar, ...Cells 10 (1), 54, 2020202
58
2020
Stem cell therapy for preventing neonatal diseases in the 21st century: current understanding and challenges
CR Nitkin, J Rajasingh, C Pisano, GE Besner, B Thébaud, V SampathPediatric research 87 (2), 265-276, 2020202
53
2020
Epigenetic dysfunctional diseases and therapy for infection and inflammation
S Samanta, S Rajasingh, T Cao, B Dawn, J RajasinghBiochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (2), 518-528, 2017201
45
2017
Optical-flow based non-invasive analysis of cardiomyocyte contractility
A Czirok, DG Isai, E Kosa, S Rajasingh, W Kinsey, Z Neufeld, J RajasinghScientific reports 7 (1), 10404, 2017201
43
2017
DNMT and HDAC inhibitors together abrogate endotoxemia mediated macrophage death by STAT3-JMJD3 signaling
S Samanta, Z Zhou, S Rajasingh, A Panda, V Sampath, J RajasinghThe international journal of biochemistry & cell biology 102, 117-127, 2018201
35
2018
Biology and clinical relevance of noncoding sno/scaRNAs
T Cao, S Rajasingh, S Samanta, B Dawn, DC Bittel, J RajasinghTrends in cardiovascular medicine 28 (2), 81-90, 2018201
30
2018
Histone deacetylase 6 regulates endothelial MyD88-dependent canonical TLR signaling, lung inflammation, and alveolar remodeling in the developing lung
H Menden, S Xia, SM Mabry, J Noel-MacDonnell, J Rajasingh, SQ Ye, ...American journal of physiology-lung cellular and molecular physiology 317 (3 …, 2019201
29
2019
Exosomes: Outlook for future cell-free cardiovascular disease therapy
B Barani, S Rajasingh, J RajasinghExosomes in cardiovascular diseases: biomarkers, pathological and …, 2017201
18
2017
Use of oral steroid and its effects on atrial fibrillation recurrence and inflammatory cytokines post ablation–the steroid AF study
S Iskandar, M Reddy, MR Afzal, J Rajasingh, M Atoui, M Lavu, D Atkins, ...Journal of atrial fibrillation 9 (5), 202
17
2017
Stem cell-derived exosomes potential therapeutic roles in cardiovascular diseases
S Jayaraman, D Gnanasampanthapandian, J Rajasingh, K PalaniyandiFrontiers in cardiovascular medicine 8, 723236, 2021202
15
2021
Comparative analysis of human induced pluripotent stem cell‐derived mesenchymal stem cells and umbilical cord mesenchymal stem cells
S Rajasingh, V Sigamani, V Selvam, N Gurusamy, S Kirankumar, ...Journal of Cellular and Molecular Medicine 25 (18), 8904-8919, 2021202
12
2021
Manipulation-free cultures of human iPSC-derived cardiomyocytes offer a novel screening method for cardiotoxicity
S Rajasingh, DG Isai, S Samanta, Z Zhou, B Dawn, WH Kinsey, A Czirok, ...Acta Pharmacologica Sinica 39 (10), 1590-1603, 2018201
11
2018
Modern approaches on stem cells and scaffolding technology for osteogenic differentiation and regeneration
S Kirankumar, N Gurusamy, S Rajasingh, V Sigamani, J Vasanthan, ...Experimental Biology and Medicine 247 (5), 433-445, 2022202
8
2022
Mesenchymal stem cell induced Foxp3 (+) Tregs suppress effector T cells and protect against retinal ischemic injury
M Agrawal, PK Rasiah, A Bajwa, J Rajasingh, R GangarajuCells 10 (11), 300, 2021202
6
2021

Referred From: https://scholar.google.com/citations?user=VXaxIcoAAAAJ&hl=en

Cited by
Citations 3357
h-index 31
i10-index 43
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