Author

Franco Laghi Pasini

Professore di Medicina Interna, Universit

Biography

Franco Laghi-Pasini or Pasini F L currently works at the Department of Medicine, Surgery and Neuroscience, Università degli Studi di Siena. Franco does research in Clinical Immunology, Internal Medicine (General Medicine) and Cardiology. His current interests are: autoimmune and inflammatory channelopathies and arrhytmic risk, purinergic modulation of fibroblast function and activation.
Title
Cited by
Year
Systemic inflammation and arrhythmic risk: lessons from rheumatoid arthritis
PE Lazzerini, PL Capecchi, F Laghi-PasiniEuropean heart journal 38 (22), 1717-1727, 2017201
282
2017
Cardioimmunology of arrhythmias: the role of autoimmune and inflammatory cardiac channelopathies
PE Lazzerini, F Laghi-Pasini, M Boutjdir, PL CapecchiNature Reviews Immunology 19 (1), 63-64, 2019201
125
2019
Interleukin-6 inhibition of hERG underlies risk for acquired long QT in cardiac and systemic inflammation
AS Aromolaran, U Srivastava, A Alí, M Chahine, D Lazaro, N El-Sherif, ...PLoS One 13 (12), e0208321, 2018201
112
2018
Systemic inflammation as a novel QT-prolonging risk factor in patients with torsades de pointes
PE Lazzerini, F Laghi-Pasini, I Bertolozzi, G Morozzi, S Lorenzini, ...Heart 103 (22), 1821-1829, 2017201
97
2017
Autoimmune channelopathies as a novel mechanism in cardiac arrhythmias
PE Lazzerini, PL Capecchi, F Laghi-Pasini, M BoutjdirNature Reviews Cardiology 14 (9), 521-535, 2017201
92
2017
Systemic Inflammation Rapidly Induces Reversible Atrial Electrical Remodeling: The Role of Interleukin‐6–Mediated Changes in Connexin Expression
PE Lazzerini, F Laghi‐Pasini, M Acampa, U Srivastava, I Bertolozzi, ...Journal of the American Heart Association 8 (16), e011006, 2019201
89
2019
Emerging arrhythmic risk of autoimmune and inflammatory cardiac channelopathies
PE Lazzerini, PL Capecchi, N El‐Sherif, F Laghi‐Pasini, M BoutjdirJournal of the American Heart Association 7 (22), e010595, 2018201
75
2018
Arrhythmogenicity of anti-Ro/SSA antibodies in patients with torsades de pointes
PE Lazzerini, Y Yue, U Srivastava, F Fabris, PL Capecchi, I Bertolozzi, ...Circulation: Arrhythmia and Electrophysiology 9 (4), e003419, 2016201
58
2016
Modulation of P2X7 receptor during inflammation in multiple sclerosis
S Amadio, C Parisi, E Piras, P Fabbrizio, S Apolloni, C Montilli, S Luchetti, ...Frontiers in immunology 8, 1529, 2017201
54
2017
Cardiac arrest risk during acute infections: systemic inflammation directly prolongs QTc interval via cytokine-mediated effects on potassium channel expression
PE Lazzerini, M Acampa, F Laghi-Pasini, I Bertolozzi, F Finizola, F Vanni, ...Circulation: Arrhythmia and Electrophysiology 13 (8), e008627, 2020202
45
2020
Proton pump inhibitors and serum magnesium levels in patients with torsades de pointes
PE Lazzerini, I Bertolozzi, F Finizola, M Acampa, M Natale, F Vanni, ...Frontiers in pharmacology 9, 363, 2018201
35
2018
Inflammatory cytokines and cardiac arrhythmias: the lesson from COVID-19
PE Lazzerini, F Laghi-Pasini, M Boutjdir, PL CapecchiNature Reviews Immunology 22 (5), 270-272, 2022202
26
2022
Spotlight on sirukumab for the treatment of rheumatoid arthritis: the evidence to date
PE Lazzerini, PL Capecchi, GM Guidelli, E Selvi, M Acampa, ...Drug design, development and therapy, 3083-3098, 2016201
25
2016
Marked QTc prolongation and torsades de pointes in patients with chronic inflammatory arthritis
PE Lazzerini, PL Capecchi, I Bertolozzi, G Morozzi, S Lorenzini, ...Frontiers in cardiovascular medicine 3, 31, 2016201
24
2016
The Safety of Adjuvanted Vaccines Revisited: Vaccine-Induced Narcolepsy.
SS Ahmed, E Montomoli, FL Pasini, L SteinmanThe Israel Medical Association Journal: IMAJ 18 (3-4), 216-220, 2016201
24
2016
Autoimmune and inflammatory K+ channelopathies in cardiac arrhythmias: Clinical evidence and molecular mechanisms
PL Capecchi, F Laghi-Pasini, N El-Sherif, Y Qu, M Boutjdir, PE LazzeriniHeart Rhythm 16 (8), 1273-1280, 2019201
23
2019
Potassium channel block and novel autoimmune-associated long QT syndrome
M Boutjdir, PE Lazzerini, PL Capecchi, F Laghi-Pasini, N El-SherifCardiac Electrophysiology Clinics 8 (2), 373-384, 2016201
22
2016
Induction of autoimmune response to the extracellular loop of the HERG channel pore induces QTc prolongation in guinea‐pigs
F Fabris, Y Yue, Y Qu, M Chahine, E Sobie, P Lee, R Wieczorek, XC Jiang, ...The Journal of Physiology 594 (21), 6175-67, 2016201
18
2016
Autoimmune calcium channelopathies and cardiac electrical abnormalities
YS Qu, PE Lazzerini, PL Capecchi, F Laghi-Pasini, N El Sherif, M BoutjdirFrontiers in cardiovascular medicine 6, 54, 2019201
17
2019
Searching novel therapeutic targets for scleroderma: P2X7-receptor is up-regulated and promotes a fibrogenic phenotype in systemic sclerosis fibroblasts
D Gentile, PE Lazzerini, A Gamberucci, M Natale, E Selvi, F Vanni, A Alì, ...Frontiers in Pharmacology 8, 638, 2017201
16
2017