Author

Benjamin J Compton

Ferrier Research Institute, Victoria University of Wellington - Cited by 564 - Carbohydrate Chemistry

Biography

Dr Benji Compton's current research focus is on developing new vaccines for malaria and influenza, as well as vaccines that can aid drug addiction. The basis of this work is his work investigating novel glycolipid compounds that modulate the human immune system. As part of a collaborative research programme with the Malaghan Institute of Medical Research, his research has helped create of new vaccine platform that instructs the immune system to "search and destroy" certain targets such as cancerous cells.
Title
Cited by
Year
A self-adjuvanting vaccine induces cytotoxic T lymphocytes that suppress allergy
RJ Anderson, C Tang, NJ Daniels, BJ Compton, CM Hayman, ...Nature chemical biology 10 (11), 943-949, 2014201
80
2014
NKT cell-dependent glycolipid–peptide vaccines with potent anti-tumour activity
RJ Anderson, BJ Compton, C Tang, A Authier-Hall, CM Hayman, ...Chemical science 6 (9), 5120-5127, 2015201
65
2015
Glycolipid-peptide vaccination induces liver-resident memory CD8+ T cells that protect against rodent malaria
LE Holz, YC Chua, MN de Menezes, RJ Anderson, SL Draper, ...Science immunology 5 (48), eaaz8035, 2020202
43
2020
Synthesis and activity of 6 ″-deoxy-6 ″-thio-α-GalCer and peptide conjugates
BJ Compton, C Tang, KA Johnston, TL Osmond, CM Hayman, DS Larsen, ...Organic Letters 17 (24), 5954-5957, 2015201
38
2015
37
2015
Augmenting influenza-specific T cell memory generation with a natural killer T cell-dependent glycolipid–peptide vaccine
RJ Anderson, J Li, L Kedzierski, BJ Compton, CM Hayman, TL Osmond, ...ACS Chemical Biology 12 (11), 2898-2905, 2017201
30
2017
An autologous leukemia cell vaccine prevents murine acute leukemia relapse after cytarabine treatment
JD Gibbins, LR Ancelet, R Weinkove, BJ Compton, GF Painter, ...Blood, The Journal of the American Society of Hematology 124 (19), 2953-2963, 2014201
25
2014
Chemical synthesis and immunosuppressive activity of dipalmitoyl phosphatidylinositol hexamannoside
GD Ainge, BJ Compton, CM Hayman, WJ Martin, SM Toms, DS Larsen, ...The Journal of Organic Chemistry 76 (12), 4941-4951, 2011201
22
2011
Glycolipid-peptide conjugate vaccines enhance CD8+ T cell responses against human viral proteins
M Speir, A Authier-Hall, CR Brooks, KJ Farrand, BJ Compton, ...Scientific reports 7 (1), 14273, 2017201
22
2017
Sesquiterpenes from the New Zealand Liverwort Lepidolaena hodgsoniae
AJ Barlow, BJ Compton, U Hertewich, SD Lorimer, RT WeaversJournal of natural products 68 (6), 825-831, 2005200
21
2005
Synthesis of the 3-methylene-2-vinyltetrahydropyran unit; the hallmark of the sesquiterpene, hodgsonox
AJ Barlow, BJ Compton, RT WeaversThe Journal of Organic Chemistry 70 (7), 2470-2475, 2005200
18
2005
18
2011
Synthesis and Toll-like receptor 4 (TLR4) activity of phosphatidylinositol dimannoside analogues
GD Ainge, WJ Martin, BJ Compton, CM Hayman, DS Larsen, S Yoon, ...Journal of medicinal chemistry 54 (20), 7268-7279, 2011201
18
2011
Synthesis and mass spectral characterization of mycobacterial phosphatidylinositol and its dimannosides
GM Rankin, BJ Compton, KA Johnston, CM Hayman, GF Painter, ...The Journal of Organic Chemistry 77 (16), 6743-6759, 2012201
18
2012
Mānuka honey-derived methylglyoxal enhances microbial sensing by mucosal-associated invariant T cells
JS Tang, BJ Compton, A Marshall, R Anderson, Y Li, H van der Woude, ...Food & function 11 (7), 5782-5787, 2020202
17
2020
Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist
BJ Compton, KJ Farrand, C Tang, TL Osmond, M Speir, A Authier-Hall, ...Organic & Biomolecular Chemistry 17 (5), 1225-1237, 2019201
16
2019
Resolution of Orthogonally Protected myo-Inositols with Novozym 435 Providing an Enantioconvergent Pathway to Ac2PIM1
AMM Lee, GF Painter, BJ Compton, DS LarsenThe Journal of Organic Chemistry 79 (22), 10916-10931, 2014201
8
2014
Physicochemical and biological characterization of synthetic phosphatidylinositol dimannosides and analogues
M Hubert, BJ Compton, CM Hayman, DS Larsen, GF Painter, T Rades, ...Molecular Pharmaceutics 10 (5), 1928-1939, 2013201
6
2013
Reactive diene for synthesis of substituted catechols
BJ Compton, DS Larsen, L Larsen, RT WeaversTetrahedron Letters 49 (2), 219-221, 2008200
6
2008