Author

Jared Rutter

Department of Biochemistry and HHMI, University of Utah - Cited by 12,180 - Metabolism - Signaling - Cancer

Biography

Jared Rutter, PhD, is a professor in the Department of Biochemistry at the University of Utah and a member of the Nuclear Control of Cell Growth and Differentiation Program at Huntsman Cancer Institute. Rutter studies how cells sense and detect energy needs for growth. Understanding the energy-sensing pathways in cells is important in cancer research because these pathways are often overactive in cancer and a good target for new chemotherapy treatments.Rutter received a bachelor's degree from Brigham Young University, Utah, and a PhD from the University of Texas Southwestern Medical Center at Dallas.
Title
Cited by
Year
The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
AA Cluntun, R Badolia, S Lettlova, KM Parnell, TS Shankar, NA Diakos, ...Cell metabolism 33 (3), 629-648. e10, 2021202
99
2021
Mitochondrial pyruvate carriers are required for myocardial stress adaptation
Y Zhang, PV Taufalele, JD Cochran, I Robillard-Frayne, JM Marx, J Soto, ...Nature metabolism 2 (11), 1248-1264, 2020202
78
2020
Mitochondrial fatty acid synthesis coordinates oxidative metabolism in mammalian mitochondria
SM Nowinski, A Solmonson, SF Rusin, JA Maschek, CL Bensard, ...Elife 9, e58041, 2020202
43
2020
The role of nonglycolytic glucose metabolism in myocardial recovery upon mechanical unloading and circulatory support in chronic heart failure
R Badolia, DKA Ramadurai, ED Abel, P Ferrin, I Taleb, TS Shankar, ...Circulation 142 (3), 259-274, 2020202
40
2020
Mitochondrial pyruvate carrier is required for optimal brown fat thermogenesis
V Panic, S Pearson, J Banks, TS Tippetts, JN Velasco-Silva, S Lee, ...Elife 9, e52558, 2020202
36
2020
Chronic cold exposure enhances glucose oxidation in brown adipose tissue
Z Wang, T Ning, A Song, J Rutter, QA Wang, L JiangEMBO reports 21 (11), e50085, 2020202
32
2020
20,000 picometers under the OMM: diving into the vastness of mitochondrial metabolite transport
CN Cunningham, J RutterEMBO reports (5), e50071, 2020202
21
2020
T cell–expressed microRNA-155 reduces lifespan in a mouse model of age-related chronic inflammation
HA Ekiz, AG Ramstead, SH Lee, MC Nelson, KM Bauer, JA Wallace, R Hu, ...The Journal of Immunology 4 (8), 64-75,
20
2020
Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism
GA Bezerra, WR Foster, HJ Bailey, KG Hicks, SW Sauer, B Dimitrov, ...IUCrJ 7 (4), 693-706, 2020202
18
2020
Protective mitochondrial fission induced by stress-responsive protein GJA1-20k
D Shimura, E Nuebel, R Baum, SE Valdez, S Xiao, JS Warren, ...Elife 10, e69207, 2021202
18
2021
The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder
E Nuebel, JT Morgan, S Fogarty, JM Winter, S Lettlova, JA Berg, YC Chen, ...EMBO reports 22 (10), e51991, 2021202
18
2021
Metabolites as signalling molecules
SA Baker, J RutterNature reviews molecular cell Biology, 1-20, 2023202
16
2023
Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency
A De La Rossa, MH Laporte, S Astori, T Marissal, S Montessuit, ...Elife 11, e72595, 2022202
13
2022
Sugar phosphate activation of the stress sensor eIF2B
Q Hao, JM Heo, BP Nocek, KG Hicks, VS Stoll, C Remarcik, S Hackett, ...Nature communications 12 (1), 3440, 2021202
13
2021
Protein-metabolite interactomics reveals novel regulation of carbohydrate metabolism
KG Hicks, AA Cluntun, HL Schubert, SR Hackett, JA Berg, PG Leonard, ...BioRxiv, 2021.08. 28.458030, 2021202
11
2021
Microglia drive pockets of neuroinflammation in middle age
EN Moca, D Lecca, KT Hope, F Etienne, AW Schaler, K Espinoza, ...Journal of Neuroscience 42 (19), 3896-3918, 2022202
10
2022
Validation of PAS kinase, a regulator of hepatic fatty acid and triglyceride synthesis, as a therapeutic target for nonalcoholic steatohepatitis
W Swiatek, KM Parnell, GA Nickols, BF Scharschmidt, J RutterHepatology Communications 4 (5), 66-707, 2020202
9
2020
Stressed to death: Mitochondrial stress responses connect respiration and apoptosis in cancer
JM Winter, T Yadav, J RutterMolecular Cell, 2022202
8
2022
Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase
KG Hicks, AA Cluntun, HL Schubert, SR Hackett, JA Berg, PG Leonard, ...Science 39 (6636), 996-1003, 2023202
7
2023
Identification of small molecule allosteric modulators of 5, 10-methylenetetrahydrofolate reductase (MTHFR) by targeting its unique regulatory domain
GA Bezerra, A Holenstein, WR Foster, B Xie, KG Hicks, C Bürer, S Lutz, ...Biochimie 183, 100-10, 2021202
7
2021

Referred From: https://scholar.google.com/citations?hl=en&user=kuT0eUYAAAAJ

Cited by
Citations 12180
h-index 50
i10-index 97
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