Author

Medini D

R3 Program Director, Wellcome Leap - Cited by 8,317 - Data Science - Vaccines - Bioinformatics - Population Genomics - Systems Biology

Biography

Medini D, GlaxoSmithKline, Vaccines Research & Development Department, Via Fiorentina 1, Italy, he Achieved Degree from University of California, Berkeley, Haas School of Business, Previously worked for Novartis Vaccines, University of Perugia, Novartis Vaccines and Diagnostics  
Title
Cited by
Year
Ten years of pan-genome analyses
G Vernikos, D Medini, DR Riley, H TettelinCurrent opinion in microbiology 23, 148-154, 2015201
472
2015
Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment
U Vogel, MK Taha, JA Vazquez, J Findlow, H Claus, P Stefanelli, ...The Lancet infectious diseases 13 (5), 416-425, 2013201
350
2013
Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines
J Donnelly, D Medini, G Boccadifuoco, A Biolchi, J Ward, C Frasch, ...Proceedings of the National Academy of Sciences 107 (45), 19490-19495, 2010201
346
2010
Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination
S Budroni, E Siena, JCD Hotopp, KL Seib, D Serruto, C Nofroni, ...Proceedings of the National Academy of Sciences 108 (11), 4494-4499, 2011201
234
2011
Bactericidal antibody against a representative epidemiological meningococcal serogroup B panel confirms that MATS underestimates 4CMenB vaccine strain coverage
G Frosi, A Biolchi, ML Sapio, F Rigat, S Gilchrist, J Lucidarme, J Findlow, ...Vaccine 31 (43), 4968-4974, 2013201
158
2013
Comparative genomics of the genus Bifidobacterium
F Bottacini, D Medini, A Pavesi, F Turroni, E Foroni, D Riley, V Giubellini, ...Microbiology 156 (11), 3243-3254, 2010201
126
2010
MATS: Global coverage estimates for 4CMenB, a novel multicomponent meningococcal B vaccine
D Medini, M Stella, J WassilVaccine 33 (23), 2629-2636, 2015201
121
2015
Comparison of open-source reverse vaccinology programs for bacterial vaccine antigen discovery
M Dalsass, A Brozzi, D Medini, R RappuoliFrontiers in immunology 10, 113, 2019201
102
2019
Diversity of Canadian meningococcal serogroup B isolates and estimated coverage by an investigational meningococcal serogroup B vaccine (4CMenB)
JA Bettinger, DW Scheifele, SA Halperin, W Vaudry, J Findlow, R Borrow, ...Vaccine 32 (1), 124-130, 2013201
99
2013
Bexsero® chronicle
G Vernikos, D MediniPathogens and global health 108 (7), 305-316, 2014201
92
2014
Interlaboratory standardization of the sandwich enzyme-linked immunosorbent assay designed for MATS, a rapid, reproducible method for estimating the strain coverage of …
BD Plikaytis, M Stella, G Boccadifuoco, LM DeTora, M Agnusdei, L Santini, ...Clinical and Vaccine Immunology 19 (10), 1609-1617, 2012201
80
2012
Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide
A Muzzi, A Brozzi, L Serino, M Bodini, R Abad, D Caugant, M Comanducci, ...Vaccine 37 (7), 991-1000, 2019201
69
2019
Early rise of blood T follicular helper cell subsets and baseline immunity as predictors of persisting late functional antibody responses to vaccination in humans
F Spensieri, E Siena, E Borgogni, L Zedda, R Cantisani, N Chiappini, ...PloS one 11 (6), e0157066, 2016201
50
2016
Potential Coverage of the 4CMenB Vaccine against Invasive Serogroup B Neisseria meningitidis Isolated from 2009 to 2013 in the Republic of Ireland
RM Mulhall, D Bennett, R Cunney, R Borrow, J Lucidarme, J Findlow, ...Msphere 3 (4), 10.1128/msphere. 00196-18, 201845201
45
2018
Meningococcal antigen typing system (MATS)-based Neisseria meningitidis serogroup B coverage prediction for the MenB-4C vaccine in the United States
G Rajam, M Stella, E Kim, S Paulos, G Boccadifuoco, L Serino, G Carlone, ...MSphere 2 (6), e00261-17, 201735201
35
2017
The challenge of post-implementation surveillance for novel meningococcal vaccines
MD Snape, D Medini, SA Halperin, L DeTora, J Drori, ER MoxonVaccine 30, B67-B72, 2012201
32
2012
The pangenome: Diversity, dynamics and evolution of genomes
H Tettelin, D MediniSpringer Nature, 2020202
29
2020
Polypeptides from neisseria meningitidis
SC Daugherty, JCD Hotopp, DR Riley, SV Angiuoli, HH Creasy, ...US Patent App. 13/199,782, 2012201
27
2012
In-silico prediction and deep-DNA sequencing validation indicate phase variation in 115 Neisseria meningitidis genes
E Siena, R D’Aurizio, D Riley, H Tettelin, S Guidotti, G Torricelli, ...BMC genomics 17 (1), 1-13, 2016201
24
2016
Pooled-sera hSBA titres predict individual seroprotection in infants and toddlers vaccinated with 4CMenB
S Budroni, A Kleinschmidt, P Boucher, D MediniVaccine 34 (23), 2579-2584, 2016201
22
2016