Author

Patrick K. Owiafe

Higher Scientific Officer - Cited by 1,378 - TB Immunology

Biography

Patrick K Owiafe been in charge of running the lab for almost 14 years and have worked with 4 fantastic line managers.Patrick K Owiafe acquired an MSc in Immunology and Immunogenetics by distance learning with the University of Manchester. In addition, all the vaccine trials that I have been part of have been successful. These include the MVA-85A TB vaccine trial, GSK M72/ASO1E and GSK Pneumococcal protein vaccine trial which is just about winding up.
Title
Cited by
Year
Recognition of Stage-Specific Mycobacterial Antigens Differentiates between Acute and Latent Infections with Mycobacterium tuberculosis
A Demissie, EMS Leyten, M Abebe, L Wassie, A Aseffa, G Abate, ...Clinical and vaccine immunology 13 (2), 179-186, 2006200
266
2006
Large-Scale Evaluation of Enzyme-Linked Immunospot Assay and Skin Test for Diagnosis of Mycobacterium tuberculosis Infection against a Gradient of Exposure …
PC Hill, RH Brookes, A Fox, K Fielding, DJ Jeffries, D Jackson-Sillah, ...Clinical Infectious Diseases 38 (7), 966-973, 2004200
242
2004
Early clinical trials with a new tuberculosis vaccine, MVA85A, in tuberculosis-endemic countries: issues in study design
HB Ibanga, RH Brookes, PC Hill, PK Owiafe, HA Fletcher, C Lienhardt, ...The Lancet Infectious Diseases 6 (8), 522-528, 2006200
93
2006
Quantitative T Cell Assay Reflects Infectious Load of Mycobacterium tuberculosis in an Endemic Case Contact Model
PC Hill, A Fox, DJ Jeffries, D Jackson-Sillah, MD Lugos, PK Owiafe, ...Clinical infectious diseases 40 (2), 273-278, 2005200
90
2005
Safety and immunogenicity of the candidate tuberculosis vaccine MVA85A in West Africa
RH Brookes, PC Hill, PK Owiafe, HB Ibanga, DJ Jeffries, SA Donkor, ...PLoS One 3 (8), e2921, 2008200
82
2008
Efficacy of a novel, protein-based pneumococcal vaccine against nasopharyngeal carriage of Streptococcus pneumoniae in infants: A phase 2, randomized …
A Odutola, MOC Ota, M Antonio, EO Ogundare, Y Saidu, E Foster-Nyarko, ...Vaccine 35 (19), 2531-2542, 2017201
77
2017
Interferon-γ ELISPOT as a biomarker of treatment efficacy in latent tuberculosis infection: a clinical trial
IM Adetifa, MOC Ota, DJ Jeffries, MD Lugos, AS Hammond, NJ Battersby, ...American journal of respiratory and critical care medicine 187 (4), 439-445, 2013201
71
2013
Immunogenicity of the tuberculosis vaccine MVA85A is reduced by coadministration with EPI vaccines in a randomized controlled trial in Gambian infants
MOC Ota, AA Odutola, PK Owiafe, S Donkor, OA Owolabi, NJ Brittain, ...Science translational medicine 3 (88), 88ra56-88ra56, 2011201
65
2011
58
2014
Reactogenicity, safety and immunogenicity of a protein-based pneumococcal vaccine in Gambian children aged 2–4 years: A phase II randomized study
A Odutola, MO Ota, EO Ogundare, M Antonio, P Owiafe, A Worwui, ...Human vaccines & immunotherapeutics 12 (2), 393-402, 2016201
41
2016
Elevated serum 25-hydroxy (OH) vitamin D levels are associated with risk of TB progression in Gambian adults
O Owolabi, S Agbla, P Owiafe, S Donkor, T Togun, AK Sillah, MOC Ota, ...Tuberculosis 98, 86-91, 2016201
29
2016
A new TB vaccine, MVA85A, induces durable antigen-specific responses 14 months after vaccination in African infants
AA Odutola, OA Owolabi, PK Owiafe, H McShane, MOC OtaVaccine 30 (38), 5591-5594, 2012201
27
2012
Broad Adaptive Immune Responses to M. tuberculosis Antigens Precede TST Conversion in Tuberculosis Exposed Household Contacts in a TB-Endemic Setting
UK Buchwald, IMO Adetifa, C Bottomley, PK Owiafe, S Donkor, AL Bojang, ...PLoS One 9 (12), e116268, 2014201
25
2014
ESAT-6 and CFP-10 can be combined to reduce the cost of testing for Mycobacterium tuberculosis infection, but CFP-10 responses associate with active disease
A Fox, DJ Jeffries, PC Hill, AS Hammond, MD Lugos, D Jackson-Sillah, ...Transactions of the Royal Society of Tropical Medicine and Hygiene 101 (7 …, 2007200
25
2007
Haematological and biochemical reference values of G ambian infants
AA Odutola, MO Afolabi, J Jafali, I Baldeh, OA Owolabi, P Owiafe, G Bah, ...Tropical medicine & international health (3), 275-283, 2014201
19
2014
Immunogenic Mycobacterium africanum strains associated with ongoing transmission in The Gambia
F Gehre, M Antonio, JK Otu, N Sallah, O Secka, T Faal, P Owiafe, ...Emerging infectious diseases 19 (10), 93, 2013201
15
2013
The effect of tuberculin skin test and BCG vaccination on the expansion of PPD-specific IFN-γ producing cells ex vivo
MOC Ota, RH Brookes, PC Hill, PK Owiafe, HB Ibanga, S Donkor, T Awine, ...Vaccine 25 (52), 8861-8867, 2007200
14
2007
Mycobacterium tuberculosis infection in close childhood contacts of adults with pulmonary tuberculosis is increased by secondhand exposure to tobacco
IMO Adetifa, L Kendall, S Donkor, MD Lugos, AS Hammond, PK Owiafe, ...The American journal of tropical medicine and hygiene 97 (2), 429, 2017201
10
2017